Statistical and computational pharmacogenomics /
Wu, Rongling
Statistical and computational pharmacogenomics / Rongling Wu, Min Lin - Boca Raton : Chapman & Hall/CRC, c2009 - 346 p. : ill. ; 25 cm. - Chapman & Hall/CRC interdisciplinary statistics series . - Interdisciplinary statistics .
Includes bibliographical references (p. 309-332) and indexes
Designs and strategies for genomic mapping and haplotyping -- Genetic haplotyping in natural populations -- Genetic haplotyping in experimental crosses -- A general genetic model for genetic haplotyping -- Basic principle of functional mapping -- Functional mapping of pharmacokinetics and pharmacodynamics -- Haplotyping drug response with a pharmacokinetics-pharmacodynamics -- Functional mapping of biological clocks -- Genetic mapping of allometric scaling -- Functional mapping of drug response with allometric scaling -- Joint functional mapping of drug efficacy and toxicity -- Modeling epistatic interactions in drug response -- Mapping genotype-environment interactions in drug response -- Nonparametric functional mapping of drug response -- Semiparametric functional mapping of drug response
9781584888284 (hardcover : alk. paper) 1584888288 (hardcover : alk. paper)
Pharmacogenetics--Statistical methods
Pharmacogenetics--Mathematical models
Pharmacogenetics--methods
Chromosome Mapping--methods
Genetic Markers
Models, Statistical
Statistical and computational pharmacogenomics / Rongling Wu, Min Lin - Boca Raton : Chapman & Hall/CRC, c2009 - 346 p. : ill. ; 25 cm. - Chapman & Hall/CRC interdisciplinary statistics series . - Interdisciplinary statistics .
Includes bibliographical references (p. 309-332) and indexes
Designs and strategies for genomic mapping and haplotyping -- Genetic haplotyping in natural populations -- Genetic haplotyping in experimental crosses -- A general genetic model for genetic haplotyping -- Basic principle of functional mapping -- Functional mapping of pharmacokinetics and pharmacodynamics -- Haplotyping drug response with a pharmacokinetics-pharmacodynamics -- Functional mapping of biological clocks -- Genetic mapping of allometric scaling -- Functional mapping of drug response with allometric scaling -- Joint functional mapping of drug efficacy and toxicity -- Modeling epistatic interactions in drug response -- Mapping genotype-environment interactions in drug response -- Nonparametric functional mapping of drug response -- Semiparametric functional mapping of drug response
9781584888284 (hardcover : alk. paper) 1584888288 (hardcover : alk. paper)
Pharmacogenetics--Statistical methods
Pharmacogenetics--Mathematical models
Pharmacogenetics--methods
Chromosome Mapping--methods
Genetic Markers
Models, Statistical