Evaluation of anticancer activities of christia vespertilionis (red butterfly wing) on breast cancer / (Record no. 104243)
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| fixed length control field | 03190ntm a2200325 i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MY-KuUP |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20260226151736.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | t||||fs|||| 000 0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | ta |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 260226t20252025my a|||fs|||| 000 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | THE0010391 (Local) |
| Qualifying information | Hardback |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | UMPSA |
| Language of cataloging | eng |
| Transcribing agency | UMPSA |
| Description conventions | rda |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sean Ng, Chee Hang, |
| Relator term | author. |
| 245 10 - TITLE STATEMENT | |
| Title | Evaluation of anticancer activities of christia vespertilionis (red butterfly wing) on breast cancer / |
| Statement of responsibility, etc. | Sean Ng Chee Hang |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Kuantan, Pahang : |
| Name of producer, publisher, distributor, manufacturer | UMPSA |
| Date of production, publication, distribution, manufacture, or copyright notice | 2025 |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | © 2025 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | xiii, 121 pages : |
| Other physical details | illustrations ; |
| 336 ## - CONTENT TYPE | |
| Source | rdacontent |
| Content type term | text |
| 337 ## - MEDIA TYPE | |
| Source | rdamedia |
| Media type term | unmediated |
| 338 ## - CARRIER TYPE | |
| Source | rdacarrier |
| Carrier type term | volume |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| Source | rda |
| File type | text file |
| Encoding format | |
| 500 ## - GENERAL NOTE | |
| General note | Faculty of Industrial Sciences and Technology |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Final Year Report (Bachelor of Applied Science in Industrial Biotechnology) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Include bibliographical reference |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Christia vespertilionis, yang dikenali sebagai "Sayap Rama-Rama Merah," tergolong dalam keluarga Fabaceae dan diiktiraf secara meluas kerana potensinya dalam perubatan tradisional, terutamanya untuk sifat anti-radang, antioksidan, dan anti-kanser. Kajian ini menyiasat kesan anti-kanser ekstrak metanol dan heksana yang diperoleh daripada daun Christia vespertilionis terhadap sel kanser payudara manusia MCF-7. Ekstrak tumbuhan diperoleh melalui kaedah maserasi dan dianalisis untuk menentukan kandungan fitokimia, termasuk fenolik, tanin, dan flavonoid yang diketahui mempunyai sifat anti-kanser. Sitotoksisiti ekstrak dinilai menggunakan ujian CCK-8 dengan kepekatan 5, 50, 100, dan 200 µg/mL dalam tempoh 24, 48, dan 72 jam. Ekstrak heksana menunjukkan aktiviti antikanser yang signifikan dengan peratusan daya hidup sel masing-masing 81.0% (24 jam), 72.9% (48 jam), dan 71.3% (72 jam) pada kepekatan 100 µg/mL. Ekstrak metanol pada kepekatan 200 µg/mL menunjukkan aktiviti sederhana dengan peratusan daya hidup sel masing-masing 82.8% (24 jam), 77.5% (48 jam), dan 83.2% (72 jam). Peratusan perencatan untuk ekstrak heksana pada kepekatan 100 µg/mL secara purata adalah 25%, menunjukkan keberkesanan yang lebih tinggi berbanding ekstrak metanol pada kepekatan 200 µg/mL, yang mencapai purata perencatan sebanyak 18.8%. Analisis fitokimia melalui Gas Chromatography-Mass Spectrometry (GC-MS) mengenal pasti sebatian utama seperti asid fenolik, flavonoid, dan alkohol rantai panjang, yang dikaitkan dengan kesan sitotoksik dan pengaruh apoptosis. Kajian ini menyimpulkan bahawa Christia vespertilionis, terutamanya ekstrak heksananya, menunjukkan potensi antikanser yang kuat terhadap sel MCF-7. Penemuan ini memastikan bahawa Christia vespertilionis merupakan agen anti-kanser semula jadi yang menjanjikan, menyokong penyelidikan lanjut untuk pengasingan sebatian bioaktif, mekanisme tindakannya, serta pengesahan keberkesanan dan keselamatan secara in-vivo. |
| 610 20 - SUBJECT ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | Faculty of Industrial Sciences and Technology |
| General subdivision | Dissertations |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Universities and colleges |
| General subdivision | Dissertations |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| General subdivision | Dissertations |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Library of Congress Classification |
| Koha item type | Final Year Report |
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