Assessment of antioxidant, anti- inflammatory and anti-bacterial properties of curcuma longa extracts using soxhlet extraction / (Record no. 105222)

MARC details
000 -LEADER
fixed length control field 03575ntm a2200349 i 4500
003 - CONTROL NUMBER IDENTIFIER
control field MY-KuUP
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20260715115527.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS
fixed length control field t|||||r|||| 000 0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field ta
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 260715t20252025my a|||fr|||| 000 0 eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number THE0010736 (Local)
Qualifying information Hardback
040 ## - CATALOGING SOURCE
Original cataloging agency UMPSA
Language of cataloging eng
Transcribing agency UMPSA
Description conventions rda
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) FTKKP .F374 2025 r Bc.
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Muhammad Farhan Naufal Bin Abdul Latiff, , ,
Relator term author.
245 10 - TITLE STATEMENT
Title Assessment of antioxidant, anti- inflammatory and anti-bacterial properties of curcuma longa extracts using soxhlet extraction /
Statement of responsibility, etc. Muhammad Farhan Naufal Bin Abdul Latiff
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Kuantan, Pahang :
Name of producer, publisher, distributor, manufacturer UMPSA,
Date of production, publication, distribution, manufacture, or copyright notice 2025
264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice © 2025
300 ## - PHYSICAL DESCRIPTION
Extent xi, 36 pages :
Other physical details illustrations ;
336 ## - CONTENT TYPE
Source rdacontent
Content type term text
337 ## - MEDIA TYPE
Source rdamedia
Media type term unmediated
338 ## - CARRIER TYPE
Source rdacarrier
Carrier type term volume
347 ## - DIGITAL FILE CHARACTERISTICS
Source rda
File type text file
Encoding format PDF
500 ## - GENERAL NOTE
General note Faculty of Chemical and Process Engineering Technology
502 ## - DISSERTATION NOTE
Dissertation note Final Year Report (Bachelor of Manufacturing Engineering Technology (Pharmaceuticals) with Hons ) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc. note Include bibliographical reference
520 3# - SUMMARY, ETC.
Summary, etc. The perennial plant Curcuma longa belongs to the Zingiberaceae family and is well known for its pharmacological properties. Historically, it has been widely used in traditional Indian medicine to treat various ailments and is now a key ingredient in modern health supplements. Its bioactive compounds, particularly curcumin, exhibit significant antibacterial, anti-inflammatory, and antioxidant effects. However, despite these known benefits, there remains a need for scientific validation regarding the best extraction methods to maximize the bioactivity of its compounds. This study focuses on the Soxhlet extraction method to evaluate the antioxidant, anti-inflammatory, and antibacterial properties of C. longa extract and its potential applications in pharmaceuticals. S. longa extract was obtained using Soxhlet extraction with ethanol as the solvent. The antioxidant activity was determined using the hydrogen peroxide (H₂O₂) free radical scavenging assay, where the IC50 value for Soxhlet extract was found to be 269 μg/mL, demonstrating notable antioxidant potential. The anti-inflammatory activity was evaluated using the bovine serum albumin (BSA) denaturation assay, with the Soxhlet extract showing an IC50 value of 301.99 μg/mL, indicating its ability to prevent protein denaturation, a key factor in inflammation. For antibacterial activity, the disc diffusion method was employed to assess inhibition against Staphylococcus aureus and Escherichia coli. The Soxhlet extract exhibited antibacterial activity against S. aureus with an inhibition zone of 4.5 mm but showed no inhibition against E. coli, likely due to the protective outer membrane of Gram-negative bacteria. The findings suggest that Soxhlet extraction is effective in extracting bioactive compounds with notable antioxidant and anti-inflammatory properties. However, its antibacterial activity is more limited, particularly against Gram-negative bacteria. These results highlight the potential of Soxhlet-extracted C. longa for pharmaceutical applications, though further optimization and research are necessary to enhance its bioactivity and therapeutic efficacy.
610 20 - SUBJECT ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element Faculty of Chemical and Process Engineering Technology
General subdivision Dissertations
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Universities and colleges
General subdivision Dissertations
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Theses
General subdivision Dissertations
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier https://umpir.ump.edu.my/id/eprint/47622
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Final Year Report
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
  Not lost Library of Congress Classification     UMPLIB GAMBANG UMPLIB GAMBANG 15/07/2026   FTKKP .F374 2025 r Bc. T000004330 15/07/2026 15/07/2026 Final Year Report

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