MARC details
| 000 -LEADER |
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| fixed length control field |
02088nam a2200265 a 4500 |
| 001 - CONTROL NUMBER |
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| control field |
vtls000066809 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
KUKTEM |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20251114204530.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
121122t2012 my a f m 000 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
THE0004453(Local) |
| 039 #9 - LEVEL OF BIBLIOGRAPHIC CONTROL AND CODING DETAIL [OBSOLETE] |
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| Level of rules in bibliographic description |
201905161548 |
| Level of effort used to assign nonsubject heading access points |
rohana |
| -- |
201211221531 |
| -- |
ida |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
UMP |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
TP248.25.S64 M67 2012 rs Bc. |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Morina Mohd Selih |
| 245 10 - TITLE STATEMENT |
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| Title |
Optimization of statin (Simvastatin) by monascus Purpureus FTC 5356 in solid-state fermentation / |
| Statement of responsibility, etc. |
a Morina Mohd Selih |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
Kuantan, Pahang : |
| Name of publisher, distributor, etc. |
UMP, |
| Date of publication, distribution, etc. |
2012 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
x, 66 p. : |
| Other physical details |
ill. ; |
| Dimensions |
30 cm. + |
| Accompanying material |
1 CD-ROM |
| 502 ## - DISSERTATION NOTE |
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| Dissertation note |
Project paper (Bachelor of Chemical Engineering (Biotechnology)) -- Universiti Malaysia Pahang - 2012 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Bibliography : p. 49-54 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Monascus sp. is a non-pathogenic fungus that can produce statin called simvastatin that can lower blood cholesterol in human body. The objective of this research is to investigate the optimization condition of the simvastatin production in solid-state fermentation by Monascus purpureus FTC 5356. The local products that used as substrates were banana, guava, pumpkin, coconut meat, corn, papaya and white rice. The fermentation was conducted using the optimum condition of 50% initial moisture content, pH6 at 30°C for 12 days in order to obtain the best substrate. Among these local products, corn can produce the simvastatin while other five fruits do not produce simvastatin. Further experimental carried out using Central Composite Design (CCD) of Response Surface Methodology (RSM) by setting two parameters which are moisture content and nitrogen source by setting the lower and higher range for each of the parameters. From the analysis from RSM, there are 14 runs conducted to achieve the optimum condition to get the maximum production of simvasatin. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Solid-state fermentation |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Enzymes |
| General subdivision |
Industrial applications |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Statins (Cardiovascular agents) |