Solid phase transformation of Carbamazepine-Saccharin (CBZ-SAC) co-crystal / (Record no. 3985)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02203nam a2200277 a 4500 |
| 001 - CONTROL NUMBER | |
| control field | vtls000075737 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | KUKTEM |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20251114204542.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 131025t2013 my da f abm 000 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | THE0003886(Local) |
| 039 #9 - LEVEL OF BIBLIOGRAPHIC CONTROL AND CODING DETAIL [OBSOLETE] | |
| Level of rules in bibliographic description | 201905161511 |
| Level of effort used to assign nonsubject heading access points | shah |
| -- | 201310251530 |
| -- | nabilah |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | UMP |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | TP156.C7 A33 2013 rs Bc. |
| 100 0# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Nur Aida Zakiriah |
| 245 10 - TITLE STATEMENT | |
| Title | Solid phase transformation of Carbamazepine-Saccharin (CBZ-SAC) co-crystal / |
| Statement of responsibility, etc. | Nur Aida Zakiriah |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Kuantan, Pahang : |
| Name of publisher, distributor, etc. | UMP, |
| Date of publication, distribution, etc. | 2013 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | xv, 70 p. : |
| Other physical details | ill. ; |
| Dimensions | 30 cm. + |
| Accompanying material | 1 CD-ROM |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Project paper (Bachelor of Chemical Engineering) -- Universiti Malaysia Pahang – 2013 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography : p. 51-52 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | A research was conducted on the solid phase transformation and stability of carbamazepine-saccharin co-crystal. Pharmaceutical co-crystal is one of the potential methods for improving the bioavailibity of drugs with low aqueous solubility. Thus, the purpose of this research is to determine the stable region of carbamazepine-saccharin (CBZ-SAC) co-crystal formation by using solution based method. In this method, three technique are used which are cooling crystallization, solvent evaporation and slurry, to prepare the chemical and use ethanol as a solvent. Different mol ratio of CBZ and SAC are being tested, in order to study CBZ-SAC cocrystal formation. Physical characterizations of the co-crystal are being characterized by differential scanning calorimetry and research microscope. Overall as the concentration of saccharin increase the melting point increase and will lead to poor solubility but mostly the melting point of co-crystal resulting in lower melting point. From this research can be concluded that CBZ-SAC co-crystal can form two forms which are plate-like and needle like. Varying the mol of carbamazepine and used different solvents could be used for further studies to see the difference trending. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Crystallization |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drugs |
| General subdivision | Solubility |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Carbamazepine |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Saccharin |
| Withdrawn status | Lost status | Damaged status | Not for loan | Home library | Current library | Date acquired | Total checkouts | Full call number | Barcode | Date last seen | Copy number | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Not lost | Not for loan | UMPLIB GAMBANG | UMPLIB GAMBANG | 04/09/2019 | TP156.C7 A33 2013 rs Bc. | 0000074627 | 04/09/2019 | 1 | 04/09/2019 | Final Year Report | |||
| Not lost | Not for loan | UMPLIB GAMBANG | UMPLIB GAMBANG | 04/09/2019 | CD 7013 | TP156.C7 A33 2013 rs Bc. | 0000074628 | 04/09/2019 | 1 | 04/09/2019 | Final Year Report |