MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02793ntm a2200289 a 4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
vtls000093952 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
KUKTEM |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20251117113347.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
160317t2015 my a f 000 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
THE0001068(Local) |
| 039 #9 - LEVEL OF BIBLIOGRAPHIC CONTROL AND CODING DETAIL [OBSOLETE] |
|---|
| Level of rules in bibliographic description |
201905171250 |
| Level of effort used to assign nonsubject heading access points |
nazirah |
| Level of effort used to assign subject headings |
201710091229 |
| Level of effort used to assign classification |
aishah |
| -- |
201603171201 |
| -- |
huda |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
UMP |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
|---|
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
FSKKP .A36 2015 r Thesis |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mohammed Adam Kunna Azrag |
| 245 1# - TITLE STATEMENT |
|---|
| Title |
Kinetic paramaters identification for large-scle metabolic model of escherichia coli / |
| Statement of responsibility, etc. |
Mohammed Adam Kunna Azrag |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Kuantan, Pahang : |
| Name of publisher, distributor, etc. |
UMP, |
| Date of publication, distribution, etc. |
2015 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
xvi, 91 p. : |
| Other physical details |
ill. ; |
| Dimensions |
30 cm. + |
| Accompanying material |
1 CD-ROM |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Faculty of Computer System and Software Engineering |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Master of Science (Compute)) -- Universiti Malaysia Pahang – 2015 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc. note |
Bibliography : p. 70-79 |
| 520 3# - SUMMARY, ETC. |
|---|
| Summary, etc. |
One of the biggest challenging in metabolic engineering is to design an accurate model of large-scale of metabolic network in metabolic engineering field; which require an appropriate sensitivity analysis and optimization techniques. This research focusing on identifying the optimize values of large-scale kinetic parameters of E. coli model. The model under study consist of five metabolic pathways which are Glycolysis, Pentose Phosphate, TCA cycle, Gluconegenesis and Glycoxylate; which contain 194 kinetic parameters to be optimize. This model also includes PTS system in addition to Acetate formation, 23 metabolites, 28 enzymatic reactions and 10 co -factors. The experimental data were run in 0.1 and 0.2 dilution rates at continuous culture on steady-state condition. The One-At-A-Time Sensitivity Measure and Particle Swarm Optimization (PSO) techniques was applied to the model under study in order to identify the optimum values of the kinetics. The result stated from the One-At-A-Time Sensitivity Measure shows that there are 7 kinetics affecting highly in the model response under 0.1 dilution rate, while in 0.2 there are 8 kinetics affecting highly in the model response also. The result stated from PSO shows that, this technique can minimize the errors of our simulation result by % as compare to (Ishii et al., 2007) and % as compare to (Hoque et al., 2005). Based on the results found by the techniques, these tichniques can be applied to correct the model response through large-scale kinetic parameters. |
| 610 20 - SUBJECT ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
Faculty of Computer System and Software Engineering |
| General subdivision |
Dissertations |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Universities and Colleges |
| General subdivision |
Dissertations |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Theses |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="http://ecollib.ump.edu.my/3619/">http://ecollib.ump.edu.my/3619/</a> |
| Public note |
Library access only |