MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03081ntm a2200373 i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
MY-KuUP |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20251125105750.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS |
|---|
| fixed length control field |
t||||fr|||| 000 0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
|---|
| fixed length control field |
ta |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
201023t2 2 m a|||fram|| 000 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
THE0008933(Local) |
| Qualifying information |
hardback |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
UMP |
| Language of cataloging |
eng |
| Transcribing agency |
UMP |
| Description conventions |
rda |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
|---|
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
FSTI .M37 2019 r Thesis |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Marina Mohd Sham, |
| Relator term |
author. |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Extraction and characterization of potential glycosaminoglycans (GAGS) from blue-spotted stingray for anticancer study / |
| Statement of responsibility, etc. |
Marina Mohd Sham |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Kuantan, Pahang : |
| Name of producer, publisher, distributor, manufacturer |
UMP, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2019 |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Date of production, publication, distribution, manufacture, or copyright notice |
© 2019 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
xiii, 89 pages : |
| Other physical details |
illustrations (some color) ; |
| Dimensions |
30 cm. + |
| Accompanying material |
1 CD-ROM |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Source |
rdacontent |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
unmediated |
| Source |
rdamedia |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computer |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
volume |
| Source |
rdacarrier |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
computer disc |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Faculty of Industrial Sciences and Technology |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Master of Science (Biotechnology)) -- Universiti Malaysia Pahang – 2019 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc. note |
Includes bibliographical references |
| 520 3# - SUMMARY, ETC. |
|---|
| Summary, etc. |
This study was carried out to find a new possible halal source of glycosaminoglycans (GAGs) for potential anticancer agent. The under-valued and rarely-bought cartilaginous Blue-spotted stingray was selected for the extraction and characterisation of GAGs. The objectives of the study are to isolate and extract the GAGs from the selected stingray and to characterise the GAGs by using characterization assay, FT-IR and NMR. Extraction was conducted to get the crude of sulfated GAGs from the Blue-spotted stingray. The crude GAGs obtained from the extraction was characterized by using Blyscan and Carbazole quantification assays. Blyscan assay result showed that the total sulfated GAGs amount obtained from the total crude GAGs is 3.9628 g. Quantification by carbazole assay strongly suggested that the crude extract contains 4.7480 g of uronic acids. The crude extract was then analysed by using Fourier Transform Infrared Resonance (FT-IR) and Nuclear Magnetic Resonance (NMR) to confirm its functional groups and molecular structures. From the FT-IR and NMR analysis, the spectra showed the presence of glycosaminoglycans in the crude extract of Blue-spotted stingray. The anticancer property of the crude extract was then studied by using human adenocarcinoma A549 (lung cancer). The results showed that crude GAGs can inhibit the A549 cells depends on the concentration used. As conclusion, blue-spotted stingray can be a halal source of potential GAGs as the yield of the crude GAGs extracted is comparable to the previous research findings. Furthermore, it showed cytotoxic property as it can inhibit the cancer cells growth. In future, the extracted GAGs from blue-spotted stingray could be a promising source of anticancer agent. |
| 610 20 - SUBJECT ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
Faculty of Industrial Sciences and Technology |
| General subdivision |
Dissertations |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Universities and colleges |
| General subdivision |
Dissertations |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Theses |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Library of Congress Classification |
| Koha item type |
Restricted Collection |