MARC details
| 000 -LEADER |
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| fixed length control field |
04035nam a2200349 i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MY-KuUP |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20251125105943.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS |
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| fixed length control field |
a||||fr|||| 001 0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
ta |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
220328t20212021my a|||fram|| 00| 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
THE0009247(Local) |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
UMP |
| Language of cataloging |
eng |
| Transcribing agency |
UMP |
| Description conventions |
rda |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
|---|
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
FTKKP .L56 2021 r Thesis |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Norlin Pauzi, |
| Relator term |
author. |
| 245 10 - TITLE STATEMENT |
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| Title |
Microwave-assisted synthesis and characterization of agglomerated zinc oxide nanoparticles stabilized with gum arabic and studies of antibacterial properties / |
| Statement of responsibility, etc. |
Norlin Pauzi |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
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| Place of production, publication, distribution, manufacture |
Kuantan, Pahang : |
| Name of producer, publisher, distributor, manufacturer |
UMP ; |
| Date of production, publication, distribution, manufacture, or copyright notice |
2021 |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
© 2021 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
xix, 157 pages : |
| Other physical details |
illustrations (some color) ; |
| Dimensions |
30 cm. + |
| Accompanying material |
1 CD-ROM. |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
unmediated |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
volume |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
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| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 500 ## - GENERAL NOTE |
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| General note |
Faculty of Chemical and Process Engineering Technology |
| 502 ## - DISSERTATION NOTE |
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| Dissertation note |
Thesis (Doctor of Philosophy) -- Universiti Malaysia Pahang – 2021 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Includes bibliographical references |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Antibacterial activity of safe and sustainable zinc oxide (ZnO) nanoparticles has huge potential in tackling antibiotic-resistant bacterial infections, especially for nano-green biomedical purposes. Various chemical methods in ZnO nanoparticles synthesis required sophisticated equipment and produce toxic as by product. It is very important to eliminate the biological risks to ensure it safe and not display unexpected side effect. The goal of this study is to investigate the effect of gum arabic on the size, optical properties, and stability of agglomerated ZnO nanoparticles and to evaluate its antibacterial properties. In this study, agglomerated ZnO nanoparticles were synthesized using a precipitating technique with the aid of a microwave heating method. Zinc nitrate had been used as salt, sodium hydroxide (NaOH) as a reducing and precipitating agent, and gum arabic as a stabilizing agent. Moreover, the effect of pH ranging from 5 to 12 on the agglomerated ZnO nanoparticle size was as well investigated. All the parameters in synthesizing agglomerated ZnO nanoparticles which include zinc salt concentration, NaOH concentration, microwave power, and microwave irradiation time were statistically optimized to achieve the smaller size of agglomerated ZnO nanoparticles; the optimization was analysed using Response Surface Methodology (RSM). The optimum agglomerated ZnO nanoparticle of 66.87 nm was achieved using gum arabic of 1.01%, 0.05 M zinc nitrate, 1.46 M NaOH, 8 min of microwave irradiation time, and 275 W of microwave heating. These agglomerated ZnO nanoparticles were relatively stabilized for a minimum of 6 months. Dynamic Light Scattering (DLS) analysis demonstrated that the hydrodynamic size was around 200 to 350 nm compared to the unstabilized agglomerated ZnO nanoparticles which were around 1020 nm. The pH value equivalent to 10 was required to attain a pure phase of ZnO nanoparticles. Additionally, stabilized agglomerated ZnO nanoparticles have better antibacterial properties on Staphylococcus aureus and Escherichia coli compared to unstabilized agglomerated ZnO nanoparticles. At a higher concentration above 500 μg/mL, the percentage of toxicity to biofilm was observed to be above 50% for both S. aureus and E. coli. Besides, agglomerated ZnO nanoparticles demonstrated antibacterial and antibiofilm activities under dark condition. However, the more effective antibacterial effect was seen in agglomerated ZnO nanoparticles under normal light. These results show that agglomerated ZnO nanoparticles can affect S. aureus and E. coli viability and biofilm formation. Therefore, agglomerated ZnO nanoparticles stabilized through gum arabic are proposed as a new naturally generated antibacterial agent. |
| 610 20 - SUBJECT ADDED ENTRY--CORPORATE NAME |
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| Corporate name or jurisdiction name as entry element |
Faculty of Chemical and Process Engineering Technology |
| General subdivision |
Dissertations |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Universities and colleges |
| General subdivision |
Dissertations |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Theses |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Library of Congress Classification |
| Koha item type |
Restricted Collection |