MARC details
| 000 -LEADER |
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| fixed length control field |
03683ntm a2200361 i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MY-KuUP |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20251125105951.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS |
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| fixed length control field |
t||||fr|||| 000 0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
220315s2021 my a|||frm||| 000 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
THE0009165(Local) |
| Qualifying information |
hardback |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
UMP |
| Language of cataloging |
eng |
| Transcribing agency |
UMP |
| Description conventions |
rda |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
|---|
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
FSTI .E83 2021 r Thesis |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Etdal Bakhiet, |
| Relator term |
author. |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Biomineralization of hydroxyethyl cellulose/sodium alginate impregnated with cellulose nanocrystals by using surface modification technique / |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Kuantan, Pahang : |
| Name of producer, publisher, distributor, manufacturer |
UMP, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2021 |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Date of production, publication, distribution, manufacture, or copyright notice |
© 2021 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
xi, 64 pages : |
| Other physical details |
illustrations ; |
| Dimensions |
30 cm. + |
| Accompanying material |
1 CD-ROM |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Source |
rdacontent |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
unmediated |
| Source |
rdamedia |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
volume |
| Source |
rdacarrier |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
computer disc |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
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| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 500 ## - GENERAL NOTE |
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| General note |
Faculty of Industrial Sciences and Technology |
| 502 ## - DISSERTATION NOTE |
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| Dissertation note |
Thesis (Master of Science ) -- Universiti Malaysia Pahang – 2021 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Includes bibliographical references |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Bone tissue engineering utilizes scaffolds fabricated from various biopolymeric materials to obtain a specific topography prior to seeding with specified cells and implantation into an injured body. The aim of this research is to synthesize biopolymeric materials from hydroxylethylcellulose (HEC) (5 wt%) blended with sodium alginate (SA)(10 wt%) at 1:1 ratio and incorporated with cellulose nanocrystals (CNC) (11 w/v%). The scaffolds was fabricated using the freeze-drying technique. For the mineralization process, these HEC/SA and HEC/SA/CNC scaffolds were treated with simulated body fluid (SBF) by immersion technique through the depositing of calcium phosphate on the scaffold’s surfaces. The behavior of scaffolds such as chemical structures and thermal properties were characterized by using FESEM, EDX, ATR-FTIR, and UTM. In-vitro biocompatibility of the scaffolds was investigated by culturing human fetal osteoblast (hFOB) cells on these scaffolds. The SEM images displayed interconnected porous structures with diameters ranging from 40 to 400 μm and porosity percentages ranging from 75 ± 5% to 90.5 ± 5 %. The high swelling ratio of HEC/SA untreated with SBF scaffold was ascribed to the strong hydrogen bonding and Van der Waals interactions between polymer chains. After 7 days of incubation, the scaffolds began to disintegrate, which leads to the increase in weight loss (simultaneously up to ~60%). ATR-FTIR results exhibit possible interactions between hydroxyl groups of HEC, SA and CNC in the blends suggests there is chemical interaction between scaffolds. The TGA results showed four different regions of mass losses, represents the degradation temperature and water disposal, side - chain bond breaking, pyrolysis of SA and dehydroxylation behavior of calcium phosphate, respectively. The cell-scaffolds interaction demonstrated that hFOB cells differentiated and spread well on the scaffolds with better cell proliferation and attachment on HEC/SA/CNC treated with SBF porous scaffolds. Since these biocompatible and biodegradable scaffolds showed promising results, these scaffolds could be adopted for the design of next-generation tissue-engineered bone grafts. |
| 610 20 - SUBJECT ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
Faculty of Industrial Sciences and Technology |
| General subdivision |
Dissertations |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Universities and colleges |
| General subdivision |
Dissertations |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Theses |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Library of Congress Classification |
| Koha item type |
Thesis |