MARC details
| 000 -LEADER |
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| fixed length control field |
04732ntm a2200373 i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MY-KuUP |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20251125110730.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS |
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| fixed length control field |
t||||fr|||| 000 0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
ta |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
230414t20232023my a|||fr|||| 000 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
THE0009456 (Local) |
| Qualifying information |
Hardback |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
UMP |
| Language of cataloging |
eng |
| Transcribing agency |
UMP |
| Description conventions |
rda |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
FTKKP .Z36 2023 r Thesis |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Muhammad Norzaman Kathiman, |
| Relator term |
author. |
| 245 10 - TITLE STATEMENT |
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| Title |
Encapsulation of mahkota dewa plant extracts using spray drying technique / |
| Statement of responsibility, etc. |
Muhammad Norzaman Kathiman |
| 264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
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| Place of production, publication, distribution, manufacture |
Pahang : |
| Name of producer, publisher, distributor, manufacturer |
UMP, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2023 |
| 264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
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| Date of production, publication, distribution, manufacture, or copyright notice |
© 2023 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
xiv, 125 pages: |
| Other physical details |
Illustration ; |
| Dimensions |
30 cm.+ |
| Accompanying material |
1 CD ROM |
| 336 ## - CONTENT TYPE |
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| Source |
rdacontent |
| Content type term |
text |
| 336 ## - CONTENT TYPE |
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| Source |
rdacontent |
| Content type term |
text |
| 337 ## - MEDIA TYPE |
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| Source |
rdamedia |
| Media type term |
unmediated |
| 337 ## - MEDIA TYPE |
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| Source |
rdamedia |
| Media type term |
computer |
| 338 ## - CARRIER TYPE |
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| Source |
rdacarrier |
| Carrier type term |
volume |
| 338 ## - CARRIER TYPE |
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| Source |
rdacarrier |
| Carrier type term |
computer disc |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
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| Source |
rda |
| File type |
text file |
| Encoding format |
PDF |
| 500 ## - GENERAL NOTE |
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| General note |
Faculty of Chemical and Process Engineering Technology |
| 502 ## - DISSERTATION NOTE |
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| Dissertation note |
Thesis (Master of Science) -- Universiti Malaysia Pahang – 2023 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Includes bibliographical reference |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Mahkota Dewa or Phaleria Macrocarpa (Scheff.) Boerl belongs to the Thymelaeaceae family and is one of the famous herbal medicines used by local people as a complementary alternative medicine for diabetes mellitus, cancer and hypertension. Currently, encapsulation using a spray drying technique protects the bioactive ingredient from thermal degradation during production and improves the shelf life. This work aims to screen and optimise the process parameters affecting the encapsulation of Mahkota Dewa fruit extracts using the spray-drying technique. One-Factor-At-A-Time (OFAT) was used to investigate the inlet air-dry temperatures (100-200˚C), feed flow rates (485-2115 mL/hr), air-dry flow rates (3.5-4.3 m/s) and encapsulation agents (maltodextrin, arabic gum and 50% maltodextrin-arabic gum) on the DPPH inhibition, moisture content and particle size distribution of spray dried powder. Then, Faced-Centred-Composite Design (FCCCD) from response surface methodology (RSM) were employed to optimise the parameters. The spray dried powder obtained at optimised conditions was further characterised using a moisture analyser, mastersizer, high performance liquid chromatography (HPLC), scanning electron microscopy (SEM), phenolic Folin-Ciocalteu assay, 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay and anti-diabetic activity (ADA) analysis. OFAT study showed that the inlet air-dry temperature, feed pump flow rate, air-dry flow rate and encapsulation agent affected the amount of dried powder produced and its physicochemical properties. Lower moisture content and smaller powder particle size with higher antioxidant activity were produced at higher inlet air-dry temperature, lower feed pump flow rate and higher air-dry flow rate. The inlet air-dry temperature (200˚C), feed pump flow rate (485 mL/hr) and air-dry flow rate (3.7 m/s) show the highest amount of spray dried powder product produced. The moisture content, mean particle size and antioxidant activity were 4.88%, 8.145 μm and 91.4277 %, respectively. The encapsulation with the combination of arabic gum and maltodextrin showed a better physicochemical property. The moisture content, mean particle size and antioxidant activity were 6.67%, 10.38 μm and 91.4087%, respectively. The optimised conditions obtained using the FCCCD method were 194.98°C inlet air-dry temperature, 447.28 mL/hr feed flow rate and 3.75 air-dry flow rate with 5.19% moisture content and 92.10% antioxidant activity. The characterisations of optimised microcapsules using SEM showed irregular shape, no open pores on the surface and significant shrinking effect. The antioxidant activities, total phenolic content and mangiferin yield were 92.10%, 0.65635 ± 0.0392 mg GAE/mg sample and 16.87 ± 2.35, respectively. The values are higher than those obtained from the OFAT and spray drying process without encapsulation. The anti-diabetic analysis confirms that Mahkota Dewa Fruit extract and optimised microcapsules exert insulin sensitising activity in the same manner as rosiglitazone does and therefore, can become a potential antidiabetic substances. In conclusion, this work successfully screened and optimised the encapsulation of Mahkota Dewa extracts into dried powder form using the spray drying technique. The outcome provides the suitable inlet air temperature, feed pump flow rate, dry air flow rate and type of carrier for spray drying of Mahkota Dewa extract. |
| 610 20 - SUBJECT ADDED ENTRY--CORPORATE NAME |
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| Corporate name or jurisdiction name as entry element |
Faculty of Chemical and Process Engineering Technology |
| General subdivision |
Dissertations |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Universities and colleges |
| General subdivision |
Dissertations |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Thesis |
| General subdivision |
Dissertations |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Library of Congress Classification |
| Koha item type |
Thesis |