Protein folding and metal ions : mechanisms, biology and disease / edited by Cláudio M. Gomes, Pernilla Wittung-Stafshede

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Material type: Text

TextPublication details: Boca Raton, FL : CRC Press, 2011Description: xiv, 294 p. : ill. ; 25 cmISBN:

9781439809648
143980964X

Subject(s):

Contents:

Chapter 1. Metal Ions, Protein Folding, and Conformational States: An Introduction / Cláudio M. Gomes and Pernilla Wittung-Stafshede -- Chapter 2. The Folding Mechanism of c-Type Cytochromes / Carlo Travaglini-Allocatelli, Stefano Gianni, and Maurizio Brunori -- Chapter 3. The Mechanism of Cytochrome C Folding: Early Events and Kinetic Intermediates / Eefei Chen, Robert A. Goldbeck, and David S. Kliger -- Chapter 4. Stability and Folding of Copper-Binding Proteins / Irina Pozdnyakova and Pernilla Wittung-Stafshede -- Chapter 5. Iron-Sulfur Clusters, Protein Folds, and Ferredoxin Stability / Sónia S. Leal and Cláudio M. Gomes -- Chapter 6. Folding and Stability of Myoglobins and Hemoglobins / David S. Culbertson and John S. Olson -- Chapter 7. Frataxin: An Unusual Metal-Binding Protein in Search of a Function / Annalisa Pastore -- Chapter 8. Mechanism of Human Copper Transporter Wilson's Disease Protein -- Amanda Barry, Zara Akram, and Svetlana Lutsenko -- Chapter 9. a-Synuclein and Metals -- Aaron Santner and Vladimir N. Uversky -- Chapter 10. Zinc and Misfolding / James S. Butler and Stewart N. Loh -- Chapter 11. The Octarepeat Domain of the Prion Protein and Its Role in Metal Ion Coordination and Disease / Glenn L. Millhauser -- Chapter 12. Metallopeptides as Tools to Understand Metalloprotein Folding and Stability / Brian R. Gibney -- Chapter 13. The Folding Landscapes of Metalloproteins / Patrick Weinkam and Peter G. Wolynes

Summary: "Interest in the uses and applications of metallo-chemistry in the life sciences continues to expand. This book provides a broad overview of metals and protein folding. It addresses fundamental aspects of the folding, stability, and design of metal binding proteins and peptides along with biological aspects related to the action of metallochaperones. The text features practical information related to methodologies, particular techniques, and bibliographic references. Readers will gain the molecular basis for protein-metal interactions and a good perspective on the applications of protein coordination chemistry in life sciences and biotechnology"--Provided by publisher

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Holdings ( 1 )
Title notes ( 3 )

Holdings
Item type	Current library	Call number	Copy number	Status	Date due	Barcode
Open Shelf	UMPLIB GAMBANG	QP552.M46 P76 2011 (Browse shelf(Opens below))	1	Available		0000062550

Includes bibliographical references and index

"Interest in the uses and applications of metallo-chemistry in the life sciences continues to expand. This book provides a broad overview of metals and protein folding. It addresses fundamental aspects of the folding, stability, and design of metal binding proteins and peptides along with biological aspects related to the action of metallochaperones. The text features practical information related to methodologies, particular techniques, and bibliographic references. Readers will gain the molecular basis for protein-metal interactions and a good perspective on the applications of protein coordination chemistry in life sciences and biotechnology"--Provided by publisher