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Extraction of bioactive compounds (mangiferin) from mahkota dewa fruits using subcritical water extraction process / Ummi Najihah Md Hashim

By:

Ummi Najihah Md Hashim [author.]

Material type: Text

text
text

Media type:

unmediated
computer

Carrier type:

volume
computer dics

ISBN:

THE0001040(Local)

Subject(s):

Dissertation note: Project Paper (Bachelor of Chemical Engineering) -- Universiti Malaysia Pahang – 2017 Abstract: Mahkota Dewa or scientifically known as Phaleria Macrocarpa is a popular herbal plant in Indonesia and Malaysia. The bioactive ingredient in this plant process antihistamine, antioxidant, anti-cancer compound. In this work, experimental studies were performed using subcritical water extraction process to extract the bioactive compound namely mangiferin from Mahkota Dewa fruits. The effect of process parameters which are solid to solvent ratios (30, 40, 50, 60, and 70 g/L), temperature (50, 75, 100, 125, 150 °C) and extraction time (3, 4, 5, 6, 7 h) on the extraction yields were investigated. The extraction yields were analysed and characterised using high performance liquid chromatography (HPLC) and 1,1-Diphenyl-2-picryl hydrazyl (DPPH) assay method, respectively. The highest mangiferin yield is 3.2027w/w % were obtained at 60 g/L of solid to solvent ratio, 100 °C of extraction temperature and 5 h of extraction time. The highest of antioxidant activity is 86.5377 % were obtained at 60 g/L of solid to solvent ratio, 125 °C of extraction temperature, 5 h of extraction time. Antioxidant is defined as a substance which significantly delays or inhibits oxidant process. The high value of antioxidant was obtained from the highest value of DPPH since the remaining DPPH in sample acts free radicals were increased in reactivity of unpaired electron and allowed the development of tissues damage in living organisms.

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Holdings ( 2 )
Title notes ( 4 )

Holdings
Item type	Current library	Call number	Copy number	Status	Date due	Barcode
Final Year Report	UMPLIB GAMBANG	FKKSA .U46 2017 r Bc. (Browse shelf(Opens below))	1	Not for loan		0000122192
Final Year Report	UMPLIB GAMBANG	CD 11176 \| FKKSA .U46 2017 r Bc. (Browse shelf(Opens below))	1	Not for loan		0000122193

Faculty of Chemical & Natural Resources Engineering

Project Paper (Bachelor of Chemical Engineering) -- Universiti Malaysia Pahang – 2017

Includes bibliographical references

Mahkota Dewa or scientifically known as Phaleria Macrocarpa is a popular herbal plant in Indonesia and Malaysia. The bioactive ingredient in this plant process antihistamine, antioxidant, anti-cancer compound. In this work, experimental studies were performed using subcritical water extraction process to extract the bioactive compound namely mangiferin from Mahkota Dewa fruits. The effect of process parameters which are solid to solvent ratios (30, 40, 50, 60, and 70 g/L), temperature (50, 75, 100, 125, 150 °C) and extraction time (3, 4, 5, 6, 7 h) on the extraction yields were investigated. The extraction yields were analysed and characterised using high performance liquid chromatography (HPLC) and 1,1-Diphenyl-2-picryl hydrazyl (DPPH) assay method, respectively. The highest mangiferin yield is 3.2027w/w % were obtained at 60 g/L of solid to solvent ratio, 100 °C of extraction temperature and 5 h of extraction time. The highest of antioxidant activity is 86.5377 % were obtained at 60 g/L of solid to solvent ratio, 125 °C of extraction temperature, 5 h of extraction time. Antioxidant is defined as a substance which significantly delays or inhibits oxidant process. The high value of antioxidant was obtained from the highest value of DPPH since the remaining DPPH in sample acts free radicals were increased in reactivity of unpaired electron and allowed the development of tissues damage in living organisms.