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Extraction of polyphenol from phyllanthus niruri / Kee Keing Lee

By:

Kee, Keing Lee [author.]

Material type: Text

text
text

Media type:

unmediated
computer

Carrier type:

volume
computer disc

ISBN:

THE0000930(Local)

Subject(s):

Dissertation note: Project Paper (Bachelor of Chemical Engineering) -- Universiti Malaysia Pahang – 2017 Abstract: Phyllanthus niruri which is also known as Dukung Anak is a plant which contain miscellaneous bioactive components which provide the medical effects such as antioxidant, anti-cancer and treating Hepatitis-B. Extraction is a common method to obtain bioactive component from plant materials therefore this research is to elucidate the effect of solvents types and investigate the performance of different type extraction method on P.Niruri. Ultrasonic assisted extraction and microwave assisted extraction methods were studied because there is no previous work found in literature. Analysis such as Total Phenolic Content, Total Flavonoids Content, Ultra-Performance Liquid Chromatography were carried out throughout the research. From the works, it is found that highest yield of phyllanthin with 4.56mg Phy/g DW was obtained with 20% aqueous Isopropanol whereas the quercetin with the highest yield, 10.14mg Que/g DW in 20% aqueous ethanol and the highest yield 15.44mg GAE/g DW of gallic acid was obtained by using water. Central Composite Design analysis shown that microware assisted extraction with 250W power, 3.62 minutes and 52.58% ethanol concentration obtain the optimum yield of polyphenol extraction of 83.70%. In conclusion, the yield of bioactive component is highly dependent on solvent polarity used in extraction and microwave extraction method provides a fast extraction without significantly compromising the extraction yield compare to ultrasonic assisted extraction.

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Holdings ( 2 )
Title notes ( 4 )

Holdings
Item type	Current library	Call number	Copy number	Status	Date due	Barcode
Final Year Report	UMPLIB GAMBANG	FKKSA .K44 2017 r Bc. (Browse shelf(Opens below))	1	Not for loan		0000122220
Final Year Report	UMPLIB GAMBANG	CD 11190 \| FKKSA .K44 2017 r Bc. (Browse shelf(Opens below))	1	Not for loan		0000122221

Faculty of Chemical & Natural Resources Engineering

Project Paper (Bachelor of Chemical Engineering) -- Universiti Malaysia Pahang – 2017

Includes bibliographical references

Phyllanthus niruri which is also known as Dukung Anak is a plant which contain miscellaneous bioactive components which provide the medical effects such as antioxidant, anti-cancer and treating Hepatitis-B. Extraction is a common method to obtain bioactive component from plant materials therefore this research is to elucidate the effect of solvents types and investigate the performance of different type extraction method on P.Niruri. Ultrasonic assisted extraction and microwave assisted extraction methods were studied because there is no previous work found in literature. Analysis such as Total Phenolic Content, Total Flavonoids Content, Ultra-Performance Liquid Chromatography were carried out throughout the research. From the works, it is found that highest yield of phyllanthin with 4.56mg Phy/g DW was obtained with 20% aqueous Isopropanol whereas the quercetin with the highest yield, 10.14mg Que/g DW in 20% aqueous ethanol and the highest yield 15.44mg GAE/g DW of gallic acid was obtained by using water. Central Composite Design analysis shown that microware assisted extraction with 250W power, 3.62 minutes and 52.58% ethanol concentration obtain the optimum yield of polyphenol extraction of 83.70%. In conclusion, the yield of bioactive component is highly dependent on solvent polarity used in extraction and microwave extraction method provides a fast extraction without significantly compromising the extraction yield compare to ultrasonic assisted extraction.