02659nam a22003017a 4500003000800000005001700008006001900025007000300044008004100047020003300088040002700121100002600148245011700174264003600291264001200327300003900339336002100378337002500399338002300424347002400447500005000471502013600521504003800657520151500695610006502210650004502275650003702320MY-KuUP20260121125201.0t||||fs|||| 000 0 ta260121t20252025my a|||fs|||| 000 0 eng d  aTHE0010294 (Local)qHardback  aUMPSAbengcUMPSAerda1 aGoh, Xue Qi,eauthor.10aEvaluation of antioxidant properties of kyllinga  nemoralis in a rat model of induced skin allergy /cGoh Xue Qi 1aKuantan, Pahang :bUMPSA,c2025 4c© 2025  axiv, 80 pages : _billustrations ;  2rdacontentatext  2rdamediaaunmediated  2rdacarrieravolume  2rdaatext filebPDF  aFaculty of Industrial Sciences and Technology  aFinal Year Report (Bachelor of Applied Science in Industrial Biotechnology) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025  aInclude bibliographical reference3 aAntioxidant properties refer to the ability of substances to neutralise or inhibit the  effects of free radicals. Free radicals can cause oxidative stress, leading to cell damage,  and inflammation. This study investigates the antioxidant properties and therapeutic  potential of Kyllinga nemoralis (K. nemoralis) methanolic extract in managing skin allergies. The study focuses on the extract's phytochemical composition, antioxidant  activity, and efficacy as an ingredient in a topical cream formulation. The phenolic  content and antioxidant activity of the K. nemoralis methanolic extract have been  evaluated by TPC and DPPH assay. The result has shown the presence of phenolic  compounds and the antioxidant activity of the crude extract and 10% K. nemoralis cream  containing the extract. The major bioactive compounds such as sesquiterpenes and  terpenoids were identified through GCMS analysis. A 10% K. nemoralis cream was  formulated as the treatment for AD-like allergy rat models induced by 2,4- dinitrochlorobenzene (DNCB). The effectiveness of the 10% K. nemoralis cream  formulated was observed on skin lesion recovery. The topical cream has shown a slight  acceleration in skin barrier recovery compared to the experimental groups which reduced  the mean scoring from 6.6 to 2.4. This indicates the treatment has enhanced the healing  of skin lesions. This study highlights the antioxidant properties of the K. nemoralis extract  with its potential therapeutic effect on AD-like skin lesions.20aFaculty of Industrial Sciences and TechnologyxDissertations 0aUniversities and collegesxDissertations 0aFinal Year ReportxDissertations