02633ntm a2200313 i 4500003000800000005001700008006001900025007000300044008004100047020003300088040002700121100003800148245013200186264003600318264001200354300003700366336002100403337002500424338002300449347002400472500005000496502013600546504003800682520140800720610006502128650004502193650003702238856004402275MY-KuUP20260126160909.0t||||fs|||| 000 0 ta260126t20252025my a|||fs|||| 000 0 eng d  aTHE0010318 (Local)qHardback  aUMPSAbengcUMPSAerda0 aNursyaemah Binti Othman,eauthor.10aEvaluation of anticancer activities of christia obcordata (stripped butterfly wing) on breast cancer /cNursyaemah Binti Othman 1aKuantan, Pahang :bUMPSA,c2025 4c© 2025  axii, 61 pages :billustrations ;  2rdacontentatext  2rdamediaaunmediated  2rdacarrieravolume  2rdaatext filebPDF  aFaculty of Industrial Sciences and Technology  aFinal Year Report (Bachelor of Applied Science in Industrial Biotechnology) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025  aInclude bibliographical reference3 aAnticancer research has advanced significantly in recent decades, with several  new anticancer medicines currently been authorized. The advancement of cancer  treatment can lead to the discovery of new therapies which are capable to maintain  momentum. The purpose of this study was to evaluate the anticancer properties of  Christia obcordata (Stripped Butterfly Wing) against breast cancer. It began with the  collection and preparation of a Christia obcordata sample, which was then subjected to  maceration extraction in triplicate to achieve total extraction of the extracts. Next,  solvent-solvent extraction was performed to get methanol and hexane extracts of Christia  obcordata, which were subsequently analysed using GC-MS to identify bioactive  components. As a vital procedure, the breast cancer cell line (MCF-7) was cultivated in  an incubator until it reached 80 to 90 percent confluency. Furthermore, cell proliferation  assays and morphological analyses were performed and monitored over a three-day  incubation period. For optimization assay, various concentrations of both extracts have  been evaluated to determine the best concentration able to inhibit cancer growth. Extracts  of methanol and hexane at 200 μg/mL yielded positive results. In conclusion, methanolic  extracts of Christia obcordata at a concentration of 200 μg/mL yielded positive findings  across three analyses.20aFaculty of Industrial Sciences and TechnologyxDissertations 0aUniversities and collegesxDissertations 0aFinal Year ReportxDissertations  uhttp://umpir.ump.edu.my/id/eprint/45696