02726ntm a2200349 i 4500 MY-KuUP 20260126160909.0 t||||fs|||| 000 0 ta 260126t20252025my a|||fs|||| 000 0 eng d THE0010318 (Local) Hardback UMPSA eng UMPSA rda FIST .E43 2025 r Bc. Nursyaemah Binti Othman, author. Evaluation of anticancer activities of christia obcordata (stripped butterfly wing) on breast cancer / Nursyaemah Binti Othman Kuantan, Pahang : UMPSA, 2025 © 2025 xii, 61 pages : illustrations ; rdacontent text rdamedia unmediated rdacarrier volume rda text file PDF Faculty of Industrial Sciences and Technology Final Year Report (Bachelor of Applied Science in Industrial Biotechnology) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025 Include bibliographical reference Anticancer research has advanced significantly in recent decades, with several new anticancer medicines currently been authorized. The advancement of cancer treatment can lead to the discovery of new therapies which are capable to maintain momentum. The purpose of this study was to evaluate the anticancer properties of Christia obcordata (Stripped Butterfly Wing) against breast cancer. It began with the collection and preparation of a Christia obcordata sample, which was then subjected to maceration extraction in triplicate to achieve total extraction of the extracts. Next, solvent-solvent extraction was performed to get methanol and hexane extracts of Christia obcordata, which were subsequently analysed using GC-MS to identify bioactive components. As a vital procedure, the breast cancer cell line (MCF-7) was cultivated in an incubator until it reached 80 to 90 percent confluency. Furthermore, cell proliferation assays and morphological analyses were performed and monitored over a three-day incubation period. For optimization assay, various concentrations of both extracts have been evaluated to determine the best concentration able to inhibit cancer growth. Extracts of methanol and hexane at 200 μg/mL yielded positive results. In conclusion, methanolic extracts of Christia obcordata at a concentration of 200 μg/mL yielded positive findings across three analyses. Faculty of Industrial Sciences and Technology Dissertations Universities and colleges Dissertations Final Year Report Dissertations http://umpir.ump.edu.my/id/eprint/45696 lcc PSM 0 0 lcc 0 0 10000 10000 2026-01-26 0 FIST .E43 2025 r Bc. T000003697 2026-01-26 16:10:30 2026-01-26 PSM 103936 103942