TY  - BOOK
AU  - P’ng Zhe Hung
TI  - Evaluation of anticancer activities  of chistia vespertilionis (red  butterfly wing) on breast cancer
SN  - THE0010324 (Local)
PY  - 2025///
CY  - Kuantan, Pahang
PB  - UMPSA
KW  - Faculty of Industrial Sciences and Technology
KW  - Dissertations
KW  - Universities and colleges
KW  - Final Year Report
N1  - Faculty of Industrial Sciences and Technology; Final Year Report (Bachelor of Applied Science in Industrial Biotechnology) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025; Include bibliographical reference
N2  - Breast cancer is a prominent cause of death in women, highlighting the need for new  therapeutic medicines. Christia vespertilionis (C. vespertilionis), which has traditionally  been used for its anti-inflammatory and antioxidant effects, may contain bioactive  chemicals that can help treat cancer. The anticancer efficacy of C. vespertilionis leaf  extracts on MCF-7 breast cancer cells were investigated in vitro using Dichloromethane  (DCM) and butanol as solvents. GC-MS study discovered bioactive substances with  anticancer and antioxidant effects, including Phytol, 6-tert-Butyl-2,4-dimethylphenol,  and n-Hexadecanoic acid. The DCM extract had a higher flavonoid content (0.5435 mg  QE/mL), but the butanol extract had a higher phenolic (0.4 mg GAE/mL) and tannin  content (0.09071 mg TAE/mL). Cytotoxicity studies revealed dose-dependent effects,  with IC50 values of 279.64 µg/mL (DCM) and 269.77 µg/mL (butanol). Apoptotic  morphological changes were seen in treated cells. These findings indicate that C.  vespertilionis leaf extracts are a potential source of natural anticancer chemicals
UR  - http://umpir.ump.edu.my/id/eprint/45705
ER  -