Kesavaraaj A/l Veerappan, <br/><br/>
Chemical compositions of different  varieties of mushrooms / 
Kesavaraaj A/l Veerappan 
 - x, 60 pages :  illustrations ; 
<br/><br/> Faculty of Industrial Sciences and Technology 
<br/><br/>Final Year Report (Bachelor of Applied Science of Industrial Chemistry) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025 
<br/><br/>Include bibliographical reference 
<br/><br/> Mushrooms are naturally derived foods that contain bioactive chemicals that may have beneficial  health effects. One of the research objectives was to determine the presence of bioactive  compounds in various mushrooms species. Besides that, this research was to determine the  correlation of various mushroom species. The area of research covered six species of mushrooms namely Pleurotus floridanus, Pleurotus ostreatus, Pleurotus pulmonarius, Pleurotus sajor-caju,  Ganoderma lucidum, and Lignosus rhinocerotis which were dried and powdered followed by  dissolving in ethanol and water. Before the samples being analyzed for their chemical  compositions by advanced techniques, UPLC-QTOF-MS analysis, the sample solution was  sonicated and centrifuged to separate the extract with the solution. Two solvent systems were used  in extracting bioactive compounds, one contains about 80% ethanol and 20% water, where a larger  spectrum of compounds extracted were observed, while the other is 100% water where the  extraction mostly favors polar molecules and therefore limit the possible bioactive substances  obtainable. The analysis highlights significant variations in compound profiles based on solvent  polarity, with ethanol-rich (80% ethanol:20% water) mixtures favoring the extraction of  hydrophobic compounds like flavonoids, triterpenoids, and phenolics, while pure water  preferentially extracts polar compounds such as glycosides and peptides. PCA results reveal that  Pearl and Indian Oyster Mushrooms in ethanol-rich solvents strongly contribute to the primary  axes of variation, reflecting their rich bioactive compound profiles. HCA further clusters  mushrooms based on their compound composition, revealing solvent-dependent grouping patterns.  Key bioactive compounds identified include 4',5,6,7-tetramethoxyflavone and cnidimol D. The  findings underscore the critical role of solvent choice in shaping the diversity and yield of bioactive  compounds, as well as the utility of multivariate analysis in unraveling complex chemical datasets.  This research not only highlights the medicinal potential of bioactive compounds from mushrooms  but also provides a methodological framework for optimizing compound extraction and profiling 
<br/><br/><label>ISBN: </label>THE0010479 (Local) 
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