03424ntm a2200337 i 4500 MY-KuUP 20261006155100.0 t||||fr|||| 000 0 ta 261006t20262026my a|||fr|||| 000 0 eng d THE0010820(Local) Hardback UMPSA eng UMPSA rda PSM .S93 2026 r Thesis Nur Syahirah Zulkipli, author. Clustering-based procedures for identifying multiple outliers in univariate circular biological data / Nur Syahirah Zulkipli Kuantan, Pahang : UMPSA 2026 © 2025 xxv, 509 pages : Illustrations ; 30 cm.+ 1 CD ROM. rdacontent text rdamedia unmediated rdacarrier volume rda text file PDF Center for Mathematical Sciences Thesis (Doctor of Philosophy) -- Universiti Malaysia Pahang - 2026 Includes bibliographical reference Circular data analysis has gained increasing attention in biological and biomedical research, particularly in improving outlier detection methods for univariate circular data. However, existing methods such as row deletion methods remain limited in detecting multiple outliers in univariate circular data. Although clustering-based procedures have been applied to bivariate circular data, their extension to univariate circular settings remains challenging due to structural differences. Hence, this study proposes a clusteringbased outlier detection (COD) procedure for univariate circular biological data using agglomerative hierarchical clustering algorithms such as single-linkage (SL), completelinkage (CL), and average-linkage (AL), combined with Satari/Di and Chang circular similarity measures to address the limitations of existing methods in detecting multiple outliers. The proposed COD procedure was evaluated through simulation studies based on the von Mises distribution under three outlier scenarios representing different contamination conditions. The findings indicate that the performance of the COD procedure is influenced by the concentration parameter, percentage of outliers and sample size. Overall, the CL-Satari/Di algorithm demonstrated strong outlier detection capability with minimal masking effects, while the SL-Satari/Di algorithm showed greater resistance to swamping effects and provided more stable performance across historical datasets. The proposed COD procedure was further validated using historical univariate circular biological datasets and syndromic craniosynostosis data in Malaysia, where it successfully identified both single and multiple outliers. Moreover, compared with existing A statistic row deletion method, the proposed COD procedure demonstrated improved capability in detecting multiple outliers while reducing masking and swamping effect. This study contributes to circular statistics methodology by extending clusteringbased outlier detection techniques to circular data, providing insight into the behaviour of masking and swamping effects in circular spaces, and also improving the understanding of contamination and cluster separability in univariate circular biological data. Center for Mathematical Sciences Dissertations Universities and colleges Dissertations Theses Dissertations lcc THESIS 0 0 lcc 0 6 REF 10000 10000 2026-10-06 0 PSM .S93 2026 r Thesis T000005624 2026-10-06 15:51:42 1 2026-10-06 THESIS 0 0 lcc 0 6 REF 10000 10000 2026-10-06 0 CD14051 T000005625 2026-10-06 15:52:15 1 2026-10-06 ACCOM 105681 105687