02735nam a2200241 a 4500 vtls000058583 KUKTEM 20251114204517.0 120306t2010 my a f m 000 0 eng d THE0004346(Local) 201905161035 rohana 201211011633 Fida 201203061138 Fida 201203061138 Fida UMP TP248.C94 A84 2010 rs Bc. Nor Ashikin Abdul Hamid Optimization of encapsulation of natural dye by cyclodextrin using response surface methodology / Nor Ashikin Binti Abdul Hamid Kuantan, Pahang : UMP, 2010 xiii, 74 p. : ill. ; 30 cm. + 1 CD-ROM Project paper (Bachelor of Chemical Engineering (Biotechnology) ) -- Universiti Malaysia Pahang - 2010 Bibliography: p. 50-55 Nowadays, cyclodextrin widely used in industries due to its ability in encapsulation process with natural dye. However, the production cost for cyclodextrin is very expensive. A study on how to reduce the production cost by optimization of pH, concentration of cyclodextrin and temperature effect on encapsulation of natural dye by cyclodextrin using Response Surface Methodology (RSM) was successfully done. During the preliminary experiment, one factor at a time was employed to screen the best range for pH, concentration of cyclodextrin and temperature. All the parameter ranges obtained were used in RSM. RSM software in Design Expert version 6.0.8 was used with Central Composite Design (CCD) mode. Seventeen sets of experiments with different parameter values were suggested by the software. The predicted optimum values for pH, concentration of cyclodextrin, temperature and concentration of encapsulation of natural dye-β-cyclodextrin were pH 3.11, 0.004 mol/L, 60 oC and 1.27763 g/L respectively. One set of experiment was run using the optimized parameter and as a result, 1.2534 g/L concentration on encapsulation of natural dye-β-cyclodextrin was recorded. Before optimization, concentration on encapsulation of natural dye-β-cyclodextrin was only 0.775 g/L and the concentration was increased by 38.17% after optimization. The optimization also reduces the cost and energy consumption as the pH reduced from pH 10.5 to pH 3.11, concentration of cyclodextrin reduced from 0.005 mol/L to 0.004 mol/L and temperature was reduced from 70 oC to 60 oC. As a conclusion, this study was successful to increase encapsulation of natural dye by cyclodextrin production, reduce the energy consumption and also be able to reduce the production cost of cyclodextrin. Cyclodextrins 0 0 0 1 10000 10000 2019-09-04 0 TP248.C94 A84 2010 rs Bc. 0000063194 2019-09-04 00:00:00 1 2019-09-04 PSM 0 0 0 6 10000 10000 2019-09-04 0 CD 5870 | TP248.C94 A84 2010 rs Bc. 0000063195 2019-09-04 00:00:00 1 2019-09-04 PSM VIRTUA40 3269 3275 VTLSSORT0080*0200*0400*0900*1000*2450*2600*3000*5020*5040*5200*6500*9992