TY - BOOK AU - Isaev,Alexander TI - Introduction to mathematical methods in bioinformatics SN - 3540219730 PY - 2004/// CY - Berlin, New York PB - Springer KW - Bioinformatics KW - Mathematics KW - Computational Biology KW - methods KW - Models, Theoretical KW - Sequence analysis N1 - Includes bibliographical references (p. [285]-288) and index; 1. Introduction : biological sequences -- 2. Sequence alignment -- 3. Markov chains and hidden Markov models -- 4. Protein folding -- 5. Phylogenetic reconstruction -- 6. Elements of probability theory -- 7. Significance of sequence alignment scores -- 8. Elements of statistics -- 9. Substitution matrices ER -