TY - BOOK AU - Mascini,Marco TI - Aptamers in bioanalysis SN - 9780470148303 (cloth) PY - 2009/// CY - Hoboken, N.J. PB - John Wiley & Sons KW - Oligonucleotides N1 - Includes bibliographical references and index; Aptamers : ligands for all reasons -- Selex and its recent optimizations -- Electrochemical aptasensors -- Aptamers : hybrids between nature and technology -- Detection of protein-aptamer interactions by means of electrochemical indicators and transverse shear mode method N2 - This is the first book to detail bioanalytical technologies and methods that have been developed using aptamers in analytical, medical, environmental, and food science applications. After an introduction to aptamers, aptamer targets, and their general uses, it discusses different applications with particular attention to the comparison between aptamer-based biosensors and methods versus the corresponding immunosensors. Examples of aptamer-based diagnostic techniques include whole-cell protein profiling (proteomics) and medical diagnostics for the distinction of diseased versus healthy states ER -