01419nam a2200205 a 4500001001400000003000700014005001700021008004100038020002200079040000800101100002900109245009300138260003400231300004500265502009200310504002800402520073400430650001401164650003501178vtls000075879KUKTEM20251114204541.0131106t2012    my da  f m    000 0 eng d  aTHE0002196(Local)  aUMP0 aMohammad Safuan Mat Noor10aMolecular dynamics simulation of ibuprofen crystal polymorph /cMohammad Safuan Mat Noor  aKuantan, Pahang :bUMP,c2012  axix, 82 p. :bill. ;c30 cm. +e1 CD-ROM  aProject paper (Bachelor of Chemical Engineering) -- Universiti Malaysia Pahang – 2012  aBibliography : p. 71-743 aIbuprofen (iso-butyl-propanolic acid) is one of the Active Pharmaceutical Ingredients (API) that uses to treat a symptom of rheumatism, arthritis, fever, as an analgesic (pain reliever). This study aims to identify which solvents should affect the polymorph of ibuprofen begins from the crystallization solution. The Molecular Dynamics Simulation and Fourier transform infrared (FTIR) is used to recognize which molecules that form hydrogen bond in the ibuprofen crystal polymorph. The study analysis has shown that the higher hydrogen bond between the atoms will contribute to the ibuprofen crystal polymorph. As the conclusion, only the selected atoms will contribute in the formation of desired crystal polymorph of ibuprofen. 0aIbuprofen 0aPolymorphism (Crystallography)