01671nam a2200253 a 4500 vtls000075879 KUKTEM 20251114204541.0 131106t2012 my da f m 000 0 eng d THE0002196(Local) 201905131716 yusri 201311121658 nabilah 201311061235 nabilah UMP QD951 .S24 2012 rs Bc. Mohammad Safuan Mat Noor Molecular dynamics simulation of ibuprofen crystal polymorph / Mohammad Safuan Mat Noor Kuantan, Pahang : UMP, 2012 xix, 82 p. : ill. ; 30 cm. + 1 CD-ROM Project paper (Bachelor of Chemical Engineering) -- Universiti Malaysia Pahang – 2012 Bibliography : p. 71-74 Ibuprofen (iso-butyl-propanolic acid) is one of the Active Pharmaceutical Ingredients (API) that uses to treat a symptom of rheumatism, arthritis, fever, as an analgesic (pain reliever). This study aims to identify which solvents should affect the polymorph of ibuprofen begins from the crystallization solution. The Molecular Dynamics Simulation and Fourier transform infrared (FTIR) is used to recognize which molecules that form hydrogen bond in the ibuprofen crystal polymorph. The study analysis has shown that the higher hydrogen bond between the atoms will contribute to the ibuprofen crystal polymorph. As the conclusion, only the selected atoms will contribute in the formation of desired crystal polymorph of ibuprofen. Ibuprofen Polymorphism (Crystallography) 0 0 0 1 10000 10000 2019-09-04 0 QD951 .S24 2012 rs Bc. 0000074783 2019-09-04 00:00:00 1 2019-09-04 PSM 0 0 0 1 10000 10000 2019-09-04 0 CD 7091 | QD951 .S24 2012 rs Bc. 0000074784 2019-09-04 00:00:00 1 2019-09-04 PSM VIRTUA40 3954 3960 VTLSSORT0080*0200*0400*0900*1000*2450*2600*3000*5020*5040*5200*6500*6501*9992