04163nam a2200325 a 4500 vtls000038039 KUKTEM 20251117145415.0 090617t2008 flua f b 001 0 eng d 9780849390067 (hbk. : alk. paper) 0849390060 (hbk. : alk. paper) 201107132138 VLOAD 200911111557 fauzi 200908141632 VLOAD 200908141606 VLOAD 200906171150 shah UMP RS403 .C43 2008 Chemistry and molecular aspects of drug design and action / [edited by] E.A. Rekka, P.N. Kourounakis Boca Raton : CRC Press/Taylor & Francis, c2008 xxii, 356 p. : ill. ; 25 cm. Includes bibliographical references and index Inflammatory mechanisms in Alzheimer's disease and other neurodegenerative disorders / Joseph Rogers ... [et al.] -- Treatment development strategies for Alzheimer's disease / Ernst Wülfert -- Lipoprotein-associated phospholipase A?b2?s as a new prognostic factor for coronary artery disease / Alexandros D. Tselepis -- New molecular targets for the prevention and treatment of gastrointestinal ulcers and inflammation / Sandor Szabo ... [et al.] -- Stress activates corticotropin releasing : factor signaling pathways : implication in functional bowel disorders / Yvette Taché -- Design, synthesis, and pharmacological evaluation of high-affinity and selectivity sigma-1 and sigma-2 receptor ligands / Jacques H. Poupaert -- Synthesis of biologically active taxoids / K.C. Nicolaou and R.K. Guy -- From the molecular pharmacology to the medicinal chemistry of cannabinoids / Didier M. Lambert -- An appraisal of fomocaines : current situation and outlook / Herbert Oelschläger and Andreas Seeling -- Ligands for the GABA recognition site at the GABAA receptor : structure-activity studies / Bente Frølund ... [et al.] -- Strategies for development of new lead structures for inhibition of acetylcholinesterase / Petra Kapkova ... [et al.] -- Discovery of potent and selective inhibitors of human aldosterone synthase (CYP11B2) : a new target for the treatment of congestive heart failure and myocardial fibrosis--a review / R.W. Hartmann ... [et al.] -- Thiocarboxanilides : a new class of nonnucleoside reverse transcriptase inhibitors (NNRTIs) with great potential for the treatment of human immunodeficiency virus type 1 (HIV-1) infections / E. De Clercq, A. Karlsson, and J. Balzarini -- Histamine H?b3?s-receptor agonists and antagonists : chemical, pharmacological, and clinical aspects / Holger Stark and Walter Schunack -- Anti-inflammatory actions of flavonoids and structural requirements for new design / Theoharis C. Theoharides -- Molecular mechanisms of H?b2?sO?b2?s-induced DNA damage : the action of desferrioxamine / M. Tenopoulou, P.-T Doulias, and D. Galaris -- LNA (locked nucleic acid) and functionalized LNA : towards efficient gene targeting / Jesper Wengel -- The effect of diet on drug metabolism / K.J. Netter -- Cytochromes P450 in the metabolism and bioactivation of chemicals / Costas Ioannides -- In vitro methods to measure drug metabolism and drug interactions in drug discovery and development / O. Pelkonen ... [et al.] -- How to probe the sites of action of drug molecules / A. Makriyannis and F. Bitter -- Physicochemical profiling in early drug discovery : new challenges at the age of high-throughput screen and combinatorial chemistry / Bernard Faller -- Drug membrane interaction and its importance for drug efficacy / J.K. Seydel ... [et al.] -- The fight against AIDS : new avenues for inhibiting reverse transcriptase (RT), and old target / Maurizio Botta ... [et al.] Pharmaceutical chemistry Drugs Design Chemistry, Pharmaceutical Drug Design Pharmacologic Actions Rekka, E. A. Kourounakis, P. N. Table of contents only http://www.loc.gov/catdir/toc/ecip0712/2007010012.html 0 0 0 0 10000 10000 2019-09-04 669.63 0 RS403 .C43 2008 0000041647 2019-09-04 00:00:00 1 669.63 2019-09-04 OPEN VIRTUA40 45591 45597 VTLSSORT0080*0200*0201*0400*0900*2450*2600*3000*5040*5050*5051*6500*6501*6502*6503*6504*7000*7001*8560*9991