TY - BOOK AU - Wu,Rongling AU - Lin,Min TI - Statistical and computational pharmacogenomics T2 - Chapman & Hall/CRC interdisciplinary statistics series SN - 9781584888284 (hardcover : alk. paper) PY - 2009/// CY - Boca Raton PB - Chapman & Hall/CRC KW - Pharmacogenetics KW - Statistical methods KW - Mathematical models KW - methods KW - Chromosome Mapping KW - Genetic Markers KW - Models, Statistical N1 - Includes bibliographical references (p. 309-332) and indexes; Designs and strategies for genomic mapping and haplotyping -- Genetic haplotyping in natural populations -- Genetic haplotyping in experimental crosses -- A general genetic model for genetic haplotyping -- Basic principle of functional mapping -- Functional mapping of pharmacokinetics and pharmacodynamics -- Haplotyping drug response with a pharmacokinetics-pharmacodynamics -- Functional mapping of biological clocks -- Genetic mapping of allometric scaling -- Functional mapping of drug response with allometric scaling -- Joint functional mapping of drug efficacy and toxicity -- Modeling epistatic interactions in drug response -- Mapping genotype-environment interactions in drug response -- Nonparametric functional mapping of drug response -- Semiparametric functional mapping of drug response UR - http://www.loc.gov/catdir/toc/ecip0814/2008013037.html ER -