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  <titleInfo>
    <title>High content screening</title>
    <subTitle>science, techniques, and applications</subTitle>
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    <title>High content screening</title>
    <subTitle>science, techniques, and applications</subTitle>
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  <name type="personal">
    <namePart>Haney, Steven A.</namePart>
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    <publisher>Wiley-Interscience</publisher>
    <dateIssued>2008</dateIssued>
    <issuance>monographic</issuance>
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    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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    <extent>xxv, 391p. : ill. ; 24 cm. + 1 computer disc</extent>
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  <tableOfContents>Approaching HCS/HCA : practical advice for users / Scott Keefer and Joseph Zock -- Automated high content screening microscopy / Paul A. Johnston -- A primer on image informatics of high content screening / Xiaobo Zhou and Stephen T.C. Wong -- Developing robust high-content assays / Arijit Chakravarty ... [et al.] -- HCS in cellular oncology / Steven A. Haney ... [et al.] -- Exploring the full power of combining high throughput RNAi with high content readouts : from target discovery screens to drug modifier studies / Christoph Sachse ... [et al.] -- Leveraging HCS in neuroscience drug discovery / Myles Fennell, Beal McIlvain &amp; John Dunlop -- Live brain slice imaging for ultra high content screening : automated fluorescent microscopy to study neurodegenerative diseases / O. Joseph Trask Jr. ... [et al.] -- High content analysis of human embryonic stem cell growth and differentiation / Paul J. Sammak ... [et al.] -- HCS for HTS / Ann F. Hoffman, Ralph J. Garippa -- The roles of high content cellular imaging in lead optimization / Jonathan A. Lee ... [et al.] -- Using high content analysis for pharmacodynamic assays in tissue / Arijit Chakravarty ... [et al.] -- High content analysis of sublethal cytotoxicity in human HepG2 hepatocytes for assessing potential and mechanism for chemical- and drug-induced human toxicity / Peter J O’Brien -- Open file formats for high-content analysis / Jason R. Swedlow ... [et al.] -- Analysis of multiparametric data / Andrew Hill ... [et al.] -- Quantitative and qualitative cellular genomics : high content analysis as an endpoint for HT-RNAi phenotype profiling using GE’s in cell platform / David O. Azorsa ... [et al.] -- Optimal characteristics of protein-protein interaction biosensors for cellular systems biology profiling / Kenneth A. Giuliano, David Premkumar, and D. Lansing Taylor.</tableOfContents>
  <targetAudience authority="marctarget">specialized</targetAudience>
  <note type="statement of responsibility">[edited by] Steven A. Haney</note>
  <subject authority="lcsh">
    <topic>Biological systems</topic>
    <topic>Research</topic>
    <topic>Methodology</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Computational Biology</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Combinatorial chemistry</topic>
  </subject>
  <identifier type="isbn">9780470039991</identifier>
  <identifier type="uri">http://www.loc.gov/catdir/enhancements/fy0801/2007027361-t.html</identifier>
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