03082nam a2200277 a 4500 vtls000057108 KUKTEM 20251117150123.0 111212t2011 flua f 001 0 eng d 9781439809648 143980964X 201202201556 asmadi 201112121449 shah UMP QP552.M46 P76 2011 Protein folding and metal ions : mechanisms, biology and disease / edited by Cláudio M. Gomes, Pernilla Wittung-Stafshede Boca Raton, FL : CRC Press, 2011 xiv, 294 p. : ill. ; 25 cm. Includes bibliographical references and index Chapter 1. Metal Ions, Protein Folding, and Conformational States: An Introduction / Cláudio M. Gomes and Pernilla Wittung-Stafshede -- Chapter 2. The Folding Mechanism of c-Type Cytochromes / Carlo Travaglini-Allocatelli, Stefano Gianni, and Maurizio Brunori -- Chapter 3. The Mechanism of Cytochrome C Folding: Early Events and Kinetic Intermediates / Eefei Chen, Robert A. Goldbeck, and David S. Kliger -- Chapter 4. Stability and Folding of Copper-Binding Proteins / Irina Pozdnyakova and Pernilla Wittung-Stafshede -- Chapter 5. Iron-Sulfur Clusters, Protein Folds, and Ferredoxin Stability / Sónia S. Leal and Cláudio M. Gomes -- Chapter 6. Folding and Stability of Myoglobins and Hemoglobins / David S. Culbertson and John S. Olson -- Chapter 7. Frataxin: An Unusual Metal-Binding Protein in Search of a Function / Annalisa Pastore -- Chapter 8. Mechanism of Human Copper Transporter Wilson's Disease Protein -- Amanda Barry, Zara Akram, and Svetlana Lutsenko -- Chapter 9. a-Synuclein and Metals -- Aaron Santner and Vladimir N. Uversky -- Chapter 10. Zinc and Misfolding / James S. Butler and Stewart N. Loh -- Chapter 11. The Octarepeat Domain of the Prion Protein and Its Role in Metal Ion Coordination and Disease / Glenn L. Millhauser -- Chapter 12. Metallopeptides as Tools to Understand Metalloprotein Folding and Stability / Brian R. Gibney -- Chapter 13. The Folding Landscapes of Metalloproteins / Patrick Weinkam and Peter G. Wolynes "Interest in the uses and applications of metallo-chemistry in the life sciences continues to expand. This book provides a broad overview of metals and protein folding. It addresses fundamental aspects of the folding, stability, and design of metal binding proteins and peptides along with biological aspects related to the action of metallochaperones. The text features practical information related to methodologies, particular techniques, and bibliographic references. Readers will gain the molecular basis for protein-metal interactions and a good perspective on the applications of protein coordination chemistry in life sciences and biotechnology"--Provided by publisher Metalloproteins Protein folding Gomes, Cláudio M. Wittung-Stafshede, Pernilla 0 0 0 0 10000 10000 2019-09-04 474.01 0 QP552.M46 P76 2011 0000062550 2019-09-04 00:00:00 1 474.01 2019-09-04 OPEN VIRTUA40 51843 51849 VTLSSORT0080*0200*0201*0400*0900*2450*2600*3000*5040*5050*5200*6500*6501*7000*7001*9991