<?xml version="1.0" encoding="UTF-8"?>
<mods xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.loc.gov/mods/v3" version="3.1" xsi:schemaLocation="http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-1.xsd">
  <titleInfo>
    <title>Computational protein-protein interactions</title>
  </titleInfo>
  <name type="personal">
    <namePart>Nussinov, Ruth.</namePart>
  </name>
  <name type="personal">
    <namePart>Schreiber, Gideon.</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">flu</placeTerm>
    </place>
    <place>
      <placeTerm type="text">Boca Raton</placeTerm>
    </place>
    <publisher>CRC Press/Taylor &amp; Francis</publisher>
    <dateIssued>2009</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="marcform">print</form>
    <extent>xvii, 317 p., [8] p. of plates : ill. (some col.) ; 25 cm.</extent>
  </physicalDescription>
  <tableOfContents>Basic principles of protein-protein interaction / Joël Janin -- Low-resolution recognition factors determine major characteristics of the energy landscape in protein-protein interaction / Ilya A. Vakser -- The molecular architecture of protein-protein binding sites / Eric J. Sundberg -- Mapping protein function by combinatorial mutagenesis / Gábor Pál and Sachdev S. Sidhu -- The association of protein-protein complexes / Gideon Schreiber -- Computational simulations of protein-protein and protein-nucleic acid association / Georgi V. Pachov, Razif R. Gabdoulline, and Rebecca C. Wade -- Computational design of protein-protein interactions / Julia M. Shifman -- Protein-protein docking / Howook Hwang, Brian Pierce, and Zhiping Weng -- Prediction of protein interaction sites / Yanay Ofran -- Predicting molecular interactions in structural proteomics / Irina Kufareva and Ruben Abagyan -- Rearrangements and expansion of the domain content in proteins frequently increase the protein connectivity in the protein-protein interaction network / Inbar Cohen-Gihon, Roded Sharan, and Ruth Nussinov -- Intrinsically disordered proteins and their recognition functions / Vladimir N. Uversky ... [et al.] -- Identification of druggable hot spots on proteins and in protein-protein interfaces / Dmitri Beglov ... [et al.] -- Designing protein-protein interaction inhibitors / Matthieu Montes</tableOfContents>
  <targetAudience authority="marctarget">specialized</targetAudience>
  <note type="statement of responsibility">edited by Ruth Nussinov, Gideon Schreiber</note>
  <note>Includes bibliographical references and index</note>
  <subject authority="lcsh">
    <topic>Protein-protein interactions</topic>
    <topic>Computer simulation</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Protein-protein interactions</topic>
    <topic>Mathematical models</topic>
  </subject>
  <subject authority="mesh">
    <topic>Protein Interaction Mapping</topic>
  </subject>
  <subject authority="mesh">
    <topic>Proteins</topic>
    <topic>physiology</topic>
  </subject>
  <subject authority="mesh">
    <topic>Computational Biology</topic>
    <topic>methods</topic>
  </subject>
  <subject authority="mesh">
    <topic>Models, Molecular</topic>
  </subject>
  <identifier type="isbn">9781420070057</identifier>
  <identifier type="isbn">1420070053</identifier>
  <recordInfo>
    <recordContentSource authority="marcorg">UMP</recordContentSource>
    <recordCreationDate encoding="marc">090818</recordCreationDate>
    <recordChangeDate encoding="iso8601">20251117150128.0</recordChangeDate>
    <recordIdentifier source="KUKTEM">vtls000041647</recordIdentifier>
  </recordInfo>
</mods>
