TY - BOOK AU - Rupp,Bernhard TI - Biomolecular crystallography: principles, practice, and application to structural biology SN - 9780815340812 PY - 2010/// CY - New York, NY PB - Garland Science KW - X-ray crystallography KW - Macromolecules KW - Structure KW - Biomolecules KW - Proteins N1 - Includes bibliographical references and index; Introduction : preparing for your study -- Protein structure -- Protein crystallization -- Proteins for crystallography -- Crystal geometry -- Diffraction basics -- Statistics and probability in crystallography -- Instrumentation and data collection -- Reconstruction of electron density and the phase problem -- Experimental phasing -- Non-crystallographic symmetry and molecular replacement -- Model building and refinement -- Structure validation, analysis, and presentatio ER -