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  <titleInfo>
    <title>Metal complex-DNA interactions</title>
  </titleInfo>
  <name type="personal">
    <namePart>Hadjiliadis, Nick D.</namePart>
  </name>
  <name type="personal">
    <namePart>Sletten, Einar</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <originInfo>
    <place>
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    <place>
      <placeTerm type="text">Chichester, West Sussex, U.K</placeTerm>
    </place>
    <publisher>Wiley</publisher>
    <dateIssued>2009</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="marcform">print</form>
    <extent>xvii, 524 p., [12] p. of plates : ill. (some col.) ; 25 cm.</extent>
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  <tableOfContents>Sequence-selective binding of transition metal complexes to DNA / Einar Sletten and Nils Åge Frøystein -- Thermodynamic models of metal ion-DNA interactions / Vasil Bregadze, Eteri Gelagutashvili and Ketevan Tsakadze -- Metal ion coordination in G-quadruplexes / Janez Plavec -- Supramolecular chemistry of metal-nucleobase complexes / P.J. Sanze Miguel ... [et al.] -- Platinum drugs, nucleotides and DNA : the role of interligand interactions / Giovanni Natile and Francesco Cannito -- Role of DNA repair in antitumour effects of platinum drugs / Viktor Brabec and Jana Kašpárková -- Telomeres and telomerase : potential targets for platinum complexes / Isabell Ourliac-Garnier, Razan Charif and Sophie Bombard -- Towards photodynamic therapy of cancer with platinum group metal polyazine complexes / David F. Zigler and Karen J. Brewer -- Platinated oligonucleotides : synthesis and applications for the control of gene expression / Vicente Marchán and Anna Grandas --</tableOfContents>
  <tableOfContents>Rhodium- and tin-DNA interactions and applications / Kenneth D. Camm and Patrick C. McGowan -- Groove-binding ruthenium(II) complexes as probes of DNA recognition / Jayden A. Smith, J. Grant Collins and F. Richard Keene -- DNA recognition and binding by peptide-metal complex conjugates / Alexandra Myari and Nick Hadjiliadis -- Artificial restriction agents : hydrolytic agents for DNA cleavage / Fabrizio Mancin and Paolo Tecilla -- New metallo-DNAzymes : fundamental studies of metal-DNA interactions and metal sensing applications / Zehui Cao and Yi Lu -- Two-metal-ion-dependent catalysis in nucleic acid enzymes / Wei Yang -- Structural studies on the mercury-mediated T-T base-pair using NMR spectroscopy / Yoshiyuki Tanaka and Akira Ono -- Chromium-induced DNA damage and repair / Laura G. Little and Kent D. Sugden -- Arsenic induced carcinogenicity : new insights in molecular mechanism / Andrea Hartwig and Tanja Schwerdtle</tableOfContents>
  <targetAudience authority="marctarget">specialized</targetAudience>
  <note type="statement of responsibility">edited by Nick Hadjiliadis and Einar Sletten</note>
  <note>Includes bibliographical references and index</note>
  <subject authority="lcsh">
    <topic>DNA-ligand interactions</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Organometallic compounds</topic>
  </subject>
  <subject authority="mesh">
    <topic>Organometallic Compounds</topic>
    <topic>chemistry</topic>
  </subject>
  <subject authority="mesh">
    <topic>Organometallic Compounds</topic>
    <topic>pharmacology</topic>
  </subject>
  <subject authority="mesh">
    <topic>Antineoplastic Agents</topic>
    <topic>therapeutic use</topic>
  </subject>
  <subject authority="mesh">
    <topic>DNA</topic>
    <topic>chemistry</topic>
  </subject>
  <subject authority="mesh">
    <topic>Metals</topic>
    <topic>therapeutic use</topic>
  </subject>
  <subject authority="mesh">
    <topic>Neoplasms</topic>
    <topic>drug therapy</topic>
  </subject>
  <identifier type="isbn">9781405176293 (cloth : alk. paper)</identifier>
  <identifier type="isbn">1405176296 (cloth : alk. paper)</identifier>
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    <recordCreationDate encoding="marc">090910</recordCreationDate>
    <recordChangeDate encoding="iso8601">20251117150458.0</recordChangeDate>
    <recordIdentifier source="KUKTEM">vtls000043758</recordIdentifier>
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