02667nam a2200253 a 4500001001400000003000700014005001700021008004100038020004300079020004000122040000800162245008700170260004000257300002900297490004800326500002500374504005000399505095600449505086401405650004902269650002802318700001902346830004802365vtls000052993KUKTEM20251117150519.0110513t2009 flua f 001 0 eng d a9781420059533 (hardcover : alk. paper) a142005953X (hardcover : alk. paper) aUMP00aHigh-throughput analysis in the pharmaceutical industry /cedited by Perry G. Wang aBoca Raton, FL :bCRC Press,cc2009 a413 p. :bill. ;c26 cm.1 aCritical reviews in combinatorial chemistry aErrata slip inserted aIncludes bibliographical references and index0 aHigh-throughput sample preparation techniques and their application to bioanalytical protocols and purification of combinatorial libraries / Krishna Kallury -- Online sample extraction coupled with multiplexing strategy to improve throughput / Katty X. Wan -- Optimizing LC/MS equipment to increase throughput in pharmaceutical analysis / Michael G. Frank and Douglas E. McIntyre -- Throughput improvement of bioanalytical LC/MS/MS by sharing detector between HPLC systems / Min Shuan Chang and Tawakol El-Shourbagy -- High-throughput strategies for metabolite identification in drug discovery / Patrick J. Rudewicz, Qin Yue, and Young Shin -- Utilizing microparallel liquid chromatography for high-throughput analyses in the pharmaceutical industry / Sergio A. Guazzotti -- Strategies and techniques for higher throughput ADME/PK assays / Walter Korfmacher -- High-throughput analysis in drug metabolism during early drug discovery / Yau Yi Lau --0 aHigh-throughput analysis in the support of process chemistry and formulation research and development in the pharmaceutical industry / Zhong Li -- Online solid phase extraction LC/MS/MS for high-throughput bioanalytical analysis / Dong Wei and Liyu Yang -- Applications of high- throughput analysis in therapeutic drug monitoring / Quanyun A. Xu and Timothy L. Madden -- High-throughput quantitative pharmaceutical analysis in drug metabolism and pharmacokinetics using liquid chromatography-mass spectrometry / Xiaohui Xu -- Designing high-throughput HPLC assays for small and biological molecules / Roger K. Gilpin and Wanlong Zhou -- Advances in capillary and nano HPLC technology for drug discovery and development / Frank J. Yang and Richard Xu -- High-throughput analysis of complex protein mixtures by mass spectrometry / Kojo S. J. Elenitoba-Johnson 0aHigh throughput screening (Drug development) 0aCombinatorial chemistry1 aWang, Perry G. 0aCritical reviews in combinatorial chemistry