02482ntm a2200229 a 4500001001400000003000700014005001700021008004100038020002200079040000800101100002800109245016200137260003400299300005700333500005000390502008400440504003000524520158800554650002102142650003202163856005702195vtls000091391KUKTEM20251117113307.0151005t2015 my a f m 000 0 eng d aTHE0002002(Local) aUMP0 aMohammad Hassan Mudaber1 aPersistency and permanency of two stages splicing languages based on DNA recombination process by using Yusof-Goode (Y-G) approach /cMohammad Hassan Mudaber aKuantan, Pahang :bUMP,c2015 axv, 120 p. :bill. (some col.) ;c30 cm. +e2 CD ROM aFaculty of Industrial Sciences and Technology aThesis (Master of Science (Mathematics)) -- Universiti Malaysia Pahang – 2015 aBibliography : p. 112-1153 aThe study of the biological process of deoxyribonucleic acid (DNA) splicing was investigated by Yusof in 2012 as a translucent approach under framework of formal languages theory. The investigation was achieved by proposing a new symbolization representing the rule in splicing system called Yusof-Goode (Y-G) rule associated with Y-G splicing system. A laboratory experiment is usually performed to show the DNA splicing process under the existence of restriction enzyme and appropriate ligase. This laboratory experiment is time consuming process and it can incur a lot of expenses. In addition, to accomplish the reaction up to two stages the generating recombining DNA molecules must have persistency concept. Thus, to overcome this problem, mathematical approach via Y-G model is applied to introduce the new concept of splicing system at two stages with respect to two initial strings and two rules. Furthermore, the existence relation between the families of stage one and stage two splicing languages are investigated. In this investigation, some sufficient conditions for persistency and permanency of two stages DNA splicing languages according to the number of cutting sites of initial strings and properties of rules are provided. The de Bruijn graph is used to predict the persistency and permanency of two stages splicing languages. A user friendly interface as an alternative of wet-lab experiment is coded using Microsoft Visual C Sharp (C#) to predict the persistency and permanency, and the relations between two stages (stage one and stage two) splicing languages. 0aFormal languages 0aDeoxyribonucleic acid (DNA)40uhttp://ecollib.ump.edu.my/3584/zLibrary access only