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  <titleInfo>
    <title>Fed-batch cultures</title>
    <subTitle>principles and applications of semi-batch bioreactors</subTitle>
  </titleInfo>
  <name type="personal">
    <namePart>Lim, Henry C.</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
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  </name>
  <name type="personal">
    <namePart>Shin, Hwa Sung</namePart>
  </name>
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  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">enk</placeTerm>
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    <place>
      <placeTerm type="text">Cambridge</placeTerm>
    </place>
    <publisher>Cambridge University Press</publisher>
    <dateIssued>2013</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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  <physicalDescription>
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    <extent>xvii, 457 p. : ill. ; 26 cm.</extent>
  </physicalDescription>
  <tableOfContents>Introduction to fed-batch bioreactors -- Idealised reactors and fed-batch reactors -- Maximisation of reaction rates and fed-batch operation -- Phenomena that favour fed-batch operations -- Classification and characteristics of fed-batch cultures -- Models based on mass balance equations -- Non-equation-based models -- Experimental determination of specific rates -- Optimization via Pontryagin’s maximum principle -- Computational techniques -- Optimization of single and multiple isothermal reactions -- Optimization of fed-batch cultures for cell mass production -- Optimization of fed-batch cultures for metabolites -- Simple, intuitive adaptive optimization -- Measurements, estimation and control -- Feasibility assessment and implementable feed rates</tableOfContents>
  <targetAudience authority="marctarget">specialized</targetAudience>
  <note type="statement of responsibility">Henry C. Lim, Hwa Sung Shin</note>
  <note>Includes bibliographical references and index</note>
  <subject authority="lcsh">
    <topic>Bioreactors</topic>
  </subject>
  <relatedItem type="series">
    <titleInfo>
      <title>Cambridge series in chemical engineering</title>
    </titleInfo>
  </relatedItem>
  <identifier type="isbn">9780521513364 (hardback)</identifier>
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    <recordCreationDate encoding="marc">131017</recordCreationDate>
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