000			02991ntm a2200337 i 4500
003			MY-KuUP
005			20260101155607.0
006			t||||fr|||| 000 0
007			ta
008			260101t20252025my a|||fr|||| 000 0 eng d
020			_aTHE0010210 (Local) _qHardback
040			_aUMPSA _beng _cUMPSA _erda
090			_aFTKMA .Z34 2025 r Thesis
100	0		_aChe Zafirah Binti Rosly, _eauthor.
245	1	0	_aPerformance comparison between iit and star protocols in managing high blood glucose incidences in three main malaysian teaching icu medical centres / _cChe Zafirah Binti Rosly
264			_aKuantan, Pahang : _bUMPSA, _c2025
264			_c© 2025
300			_axii, 87 pages : _billustrations (some color) ; _c30 cm. + _e1 CD-ROM
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
347			_2rda _atext file _bPDF
500			_aFaculty of Mechanical and Automotive Engineering Technology
502			_aThesis (Master of Science) -- Universiti Malaysia Pahang – 2025
504			_aIncludes bibliographical references
520	3		_aMalaysia has a high mortality rate in the Intensive Care Unit (ICU). Various experiments were conducted to reduce the mortality rate among critical patients in Malaysia. It is known that ICU centre in Malaysia is using intensive insulin therapy (IIT) which has successfully managed the BG level within the targeted band to achieve required safety goals. However, alterations to the current practice needed to be considered to minimize the risk of severe low BG level and mortality cases while reducing the case of severe high BG level cases. Thus, this study aims to assess the performance of a new practice is known as the Stochastic Targeted (STAR) Protocol in managing BG levels in Malaysia ICU setting and to compare its performance between the three teaching hospitals. STAR is a tablet-computer based protocol that provides a patient-specific glucose control framework accounting for patient variability with a stochastically derived maximum 5% risk of severe low blood glucose level events. The patient’s BG levels, exogenous insulin and nutrition inputs were extracted from the ICU charts to create virtual patients by using the physiologically mathematical model. Three trials were simulated with controlled goal feed (GF) and without GF. This study focused on Glucerna as the primary nutritional input. The outcomes will be compared in terms of % BG within the targeted band of 4.0 to 10.0 mmol/L. The results indicate that the STAR virtual trial with controlled GF reduced the risk of severe high BG level measurements for all cohorts with respective increases of 9.6% (HTAA), 22.6% (PPUM), and 15.1% (HUSM) of desired BG level within the safety range of 4.0-10.0mmol/L.
610	2	0	_aFaculty of Mechanical and Automotive Engineering Technology _xDissertations
650		0	_aUniversities and colleges _xDissertations
650		0	_aTheses _xDissertations
942			_2lcc _cTHESIS
999			_c103828 _d103834