000			02752nam a22003377a 4500
003			MY-KuUP
005			20260121125201.0
006			t||||fs|||| 000 0
007			ta
008			260121t20252025my a|||fs|||| 000 0 eng d
020			_aTHE0010294 (Local) _qHardback
040			_aUMPSA _beng _cUMPSA _erda
090			_aFIST .X84 2025 r Bc.
100	1		_aGoh, Xue Qi, _eauthor.
245	1	0	_aEvaluation of antioxidant properties of kyllinga nemoralis in a rat model of induced skin allergy / _cGoh Xue Qi
264		1	_aKuantan, Pahang : _bUMPSA, _c2025
264		4	_c© 2025
300			_axiv, 80 pages : _ _billustrations ;
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
347			_2rda _atext file _bPDF
500			_aFaculty of Industrial Sciences and Technology
502			_aFinal Year Report (Bachelor of Applied Science in Industrial Biotechnology) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025
504			_aInclude bibliographical reference
520	3		_aAntioxidant properties refer to the ability of substances to neutralise or inhibit the effects of free radicals. Free radicals can cause oxidative stress, leading to cell damage, and inflammation. This study investigates the antioxidant properties and therapeutic potential of Kyllinga nemoralis (K. nemoralis) methanolic extract in managing skin allergies. The study focuses on the extract's phytochemical composition, antioxidant activity, and efficacy as an ingredient in a topical cream formulation. The phenolic content and antioxidant activity of the K. nemoralis methanolic extract have been evaluated by TPC and DPPH assay. The result has shown the presence of phenolic compounds and the antioxidant activity of the crude extract and 10% K. nemoralis cream containing the extract. The major bioactive compounds such as sesquiterpenes and terpenoids were identified through GCMS analysis. A 10% K. nemoralis cream was formulated as the treatment for AD-like allergy rat models induced by 2,4- dinitrochlorobenzene (DNCB). The effectiveness of the 10% K. nemoralis cream formulated was observed on skin lesion recovery. The topical cream has shown a slight acceleration in skin barrier recovery compared to the experimental groups which reduced the mean scoring from 6.6 to 2.4. This indicates the treatment has enhanced the healing of skin lesions. This study highlights the antioxidant properties of the K. nemoralis extract with its potential therapeutic effect on AD-like skin lesions.
610	2	0	_aFaculty of Industrial Sciences and Technology _xDissertations
650		0	_aUniversities and colleges _xDissertations
650		0	_aFinal Year Report _xDissertations
942			_2lcc _cPSM
999			_c103901 _d103907