000			02726ntm a2200349 i 4500
003			MY-KuUP
005			20260126160909.0
006			t||||fs|||| 000 0
007			ta
008			260126t20252025my a|||fs|||| 000 0 eng d
020			_aTHE0010318 (Local) _qHardback
040			_aUMPSA _beng _cUMPSA _erda
090			_aFIST .E43 2025 r Bc.
100	0		_aNursyaemah Binti Othman, _eauthor.
245	1	0	_aEvaluation of anticancer activities of christia obcordata (stripped butterfly wing) on breast cancer / _cNursyaemah Binti Othman
264		1	_aKuantan, Pahang : _bUMPSA, _c2025
264		4	_c© 2025
300			_axii, 61 pages : _billustrations ;
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
347			_2rda _atext file _bPDF
500			_aFaculty of Industrial Sciences and Technology
502			_aFinal Year Report (Bachelor of Applied Science in Industrial Biotechnology) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025
504			_aInclude bibliographical reference
520	3		_aAnticancer research has advanced significantly in recent decades, with several new anticancer medicines currently been authorized. The advancement of cancer treatment can lead to the discovery of new therapies which are capable to maintain momentum. The purpose of this study was to evaluate the anticancer properties of Christia obcordata (Stripped Butterfly Wing) against breast cancer. It began with the collection and preparation of a Christia obcordata sample, which was then subjected to maceration extraction in triplicate to achieve total extraction of the extracts. Next, solvent-solvent extraction was performed to get methanol and hexane extracts of Christia obcordata, which were subsequently analysed using GC-MS to identify bioactive components. As a vital procedure, the breast cancer cell line (MCF-7) was cultivated in an incubator until it reached 80 to 90 percent confluency. Furthermore, cell proliferation assays and morphological analyses were performed and monitored over a three-day incubation period. For optimization assay, various concentrations of both extracts have been evaluated to determine the best concentration able to inhibit cancer growth. Extracts of methanol and hexane at 200 μg/mL yielded positive results. In conclusion, methanolic extracts of Christia obcordata at a concentration of 200 μg/mL yielded positive findings across three analyses.
610	2	0	_aFaculty of Industrial Sciences and Technology _xDissertations
650		0	_aUniversities and colleges _xDissertations
650		0	_aFinal Year Report _xDissertations
856			_uhttp://umpir.ump.edu.my/id/eprint/45696
942			_2lcc _cPSM
999			_c103936 _d103942