000			02678ntm a2200337 i 4500
003			MY-KuUP
005			20260302154825.0
006			t||||fr|||| 000 0
007			cr || ||||a
008			260302b |||||||| |||| 00| 0 eng d
020			_aTHE0010407 (Local) _qHardback
040			_aUMPSA _beng _cUMPSA _erda
090			_aFIST .L57 2025 r Bc.
100	1		_aLishalini K Murugan, _eauthor.
245	1	0	_aDevelopment of antibacterial film from bacterial cellulose and vitex negundo extract / _cLishalini K Murugan
264		1	_aKuantan, Pahang : _bUMPSA, _c2025
264		4	_c© 2025
300			_axiii, 103 pages : _billustrations ;
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
347			_2rda _atext file _bPDF
500			_aFaculty of Industrial Sciences and Technology
502			_aFinal Year Report (Bachelor of Applied Science in Industrial Biotechnology) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025
504			_aInclude bibliographical reference
520	3		_aThe study explores the development of antibacterial films using bacterial cellulose (BC) and Vitex negundo extract, targeting applications in wound healing and other industries. Bacterial cellulose, a biocompatible, biodegradable, and renewable polymer, serves as a structural base, while the medicinal properties of Vitex negundo, known for its antimicrobial and antioxidant activities, enhance the film’s functional properties. The Vitex negundo extract was obtained using methanol Soxhlet extraction, and BC was synthesized via fermentation of Komagataeibacter nataicola. The films were prepared by incorporating varying concentrations (0.75% and 1%) of Vitex negundo extract into an alginate-BC matrix. Characterization of the films was conducted using Fourier-transform infrared (FTIR) spectroscopy, which confirmed the presence of functional groups from the extract. Thermogravimetric analysis (TGA) demonstrated improved thermal stability with higher concentrations of Vitex negundo. The antioxidant activity, measured through DPPH assays, exhibited a concentration-dependent radical scavenging effect, with the 1% Vitex negundo film showing superior activity. Antimicrobial testing against E. coli and Bacillus revealed significant inhibitory effects, particularly at higher extract concentrations. Water sensitivity tests indicated reduced moisture content, further enhancing the film's suitability for biomedical.
610	2	0	_aFaculty of Industrial Sciences and Technology _xDissertations
650		0	_aUniversities and colleges _xDissertations
650		0	_aFinal Year Report _xDissertations
942			_2lcc _cPSM
999			_c104258 _d104264