000			03064ntm a2200349 i 4500
003			MY-KuUP
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008			260302t20252025my a|||fs|||| 000 0 eng d
020			_aTHE0010409 (Local) _qHardback
040			_aUMPSA _beng _cUMPSA _erda
090			_aFIST .H86 2025 r Bc.
100	1		_aMathumittha Tamil Selvan, _eauthor.
245	1	0	_aThe formulation and effect of tiger milk mushroom and cordyceps from hot water extraction method for therapeutic applications / _cMathumittha Tamil Selvan
264		1	_aKuantan, Pahang : _bUMPSA, _c2025
264		4	_c© 2025
300			_axiii, 70 pages : _billustrations ;
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
347			_2rda _atext file _bPDF
500			_aFaculty of Industrial Sciences and Technology
502			_aFinal Year Report (Bachelor of Applied Science in Industrial Biotechnology) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025
504			_aInclude bibliographical reference
520	3		_aThis study explores the therapeutic potential of tiger milk mushroom (Lignosus rhinocerus) and cordyceps (Cordyceps sinensis) extracts, focusing on their antiinflammatory and antioxidant properties when formulated in different ratios. Using hot water extraction, the study prepared five formulations, including pure extracts of each mushroom and combinations in ratios of 1:1, 1:2, and 2:1. These formulations were evaluated for bioactivity through assays such as Bovine Serum Albumin (BSA) denaturation for anti-inflammatory properties and DPPH radical scavenging and FRAP assays for antioxidant potential. The findings revealed that all formulations displayed significant bioactivity, with the 2:1 ratio of tiger milk mushroom to cordyceps (Formulation 5) demonstrating the highest efficacy in both its anti-inflammatory and antioxidant properties, highlighting a synergistic interaction when compared to the 1:1 and 1:2 ratios. Chemical analysis using FTIR and HPLC confirmed the presence of bioactive compounds, including phenolic acids, and other antioxidant agents, which are key contributors to the observed effects. The study underscores the synergistic potential of these mushrooms in combating oxidative stress and inflammation-related diseases, presenting a natural, low-side-effect alternative to conventional therapies. The study paves the way for the development of safe and effective natural formulations as alternatives to conventional drugs with fewer side effects. Moreover, these results offer a foundation for future research, including in vivo studies and large-scale production, to further explore and optimize these natural formulations for therapeutic use.
610	2	0	_aFaculty of Industrial Sciences and Technology _xDissertations
650		0	_aUniversities and colleges _xDissertations
650		0	_aFinal Year Report _xDissertations
856			_uhttp://umpir.ump.edu.my/id/eprint/45757
942			_2lcc _cTHESIS
999			_c104260 _d104266