000			03219ntm a2200349 i 4500
003			MY-KuUP
005			20260714153658.0
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008			260714t20252025my a|||fr|||| 000 0 eng d
020			_aTHE0010727 (Local) _qHardback
040			_aUMPSA _beng _cUMPSA _erda
090			_aFTKKP .F35 2025 r Bc.
100	1		_aFakhria Musdalifah Binti Saifullah, , , _eauthor.
245	1	0	_aEnhancement of antimicrobial properties of bacterial cellulose with chitosan for wound healing application / _cFakhria Musdalifah Binti Saifullah
264		1	_aKuantan, Pahang : _bUMPSA, _c2025
264		4	_c© 2025
300			_axi, 31 pages : _billustrations ;
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
347			_2rda _atext file _bPDF
500			_aFaculty of Chemical and Process Engineering Technology
502			_aFinal Year Report (Bachelor of Manufacturing Engineering Technology (Pharmaceuticals) with Hons ) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025
504			_aInclude bibliographical reference
520	3		_aBacterial cellulose (BC) has emerged as a highly effective material for wound dressings due to its unique structure and properties. However, BC lacks inherent antimicrobial properties, limiting its effectiveness in preventing infections This study aims to enhance the antimicrobial properties of BC by incorporating chitosan (Ch), a biodegradable polymer with inherent antimicrobial characteristics, to develop a composite optimized for wound healing applications. The BC used in this research was extracted from nata de coco, an affordable and environmentally friendly source, recognized for its exceptional purity and compatibility with biological system. The composite was produced using Ch solutions of varying concentrations (1%, 1.5%, and 2%). Analyses using Fourier Transform Infrared Spectroscopy (FTIR) and Field Emission Scanning Electron Microscopy (FESEM) confirmed the successful incorporation of Ch, which enhanced the composite's structural and chemical properties. The antimicrobial activity of the composites was evaluated using the agar diffusion method against Escherichia coli. Results showed a dose-dependent improvement in antimicrobial performance, with the BC- Ch composite at 2% Ch concentration exhibiting the largest inhibition zone of 15 mm, compared to 6 mm for pure BC. This indicates a significant enhancement in antimicrobial efficacy. In conclusion, the BC- Ch composite demonstrates strong potential as an effective and sustainable alternative to conventional wound dressings. By combining the structural benefits of BC with the antimicrobial properties of Ch, the composite addresses key challenges in wound care, offering improved infection control and wound healing capabilities. This study provides a foundation for further development of advanced, eco-friendly wound dressing materials.
610	2	0	_aFaculty of Chemical and Process Engineering Technology _xDissertations
650		0	_aUniversities and colleges _xDissertations
650		0	_aTheses _xDissertations
856			_uhttps://umpir.ump.edu.my/id/eprint/47611
942			_2lcc _cPSM
999			_c105213 _d105219