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020 _aTHE0010764 (Local)
_qHardback
040 _aUMPSA
_beng
_cUMPSA
_erda
090 _aFTKKP .M35 2025 r Bc.
100 0 _aWan Malissa Zahirah Binti Wan Mazlan, , ,
_eauthor.
245 1 0 _aFormulation of quercetin tablets :
_benhancing solubility with lactose monohydrate /
_cWan Malissa Zahirah Binti Wan Mazlan
264 1 _aKuantan, Pahang :
_bUMPSA,
_c2025
264 4 _c© 2025
300 _axi, 47 pages :
_billustrations ;
336 _2rdacontent
_atext
337 _2rdamedia
_aunmediated
338 _2rdacarrier
_avolume
347 _2rda
_atext file
_bPDF
500 _aFaculty of Chemical and Process Engineering Technology
502 _aFinal Year Report (Bachelor of Manufacturing Engineering Technology (Pharmaceutical) with Hons.) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025
504 _aInclude bibliographical reference
520 3 _aThis thesis explores the selection of concentration of lactose monohydrate for the development of quercetin supplement tablets with the aim of enhancing the solubility of quercetin tablets. Various technologies have been used to produce a quality vitamin supplement. Various research and development (R&D) processes are also carried out to obtain the best formulas and quality products. This thesis aims to find out the effectiveness of lactose monohydrate to enhance solubility of quercetin tablets. This study varying concentrations of lactose monohydrate in range 5% until 15% on the solubility, dissolution rate and physical and mechanical properties including hardness, weight variation, friability and disintegration time of quercetin tablets. The methodology encompasses assessing the granulation process by using sieve. Then, the granule went for drying process with the temperature of 50 ᵒC and lastly using the tablet press machine for tablet compression. Additionally, few testing is conducted to understand their physical and mechanical properties. The hardness testing, friability testing, weight variation, dissolution testing and disintegration testing result are recorder and compared with the standard. The result indicate 10% of lactose monohydrate as an optimal concentration due to its superior value of each testing conducted. The developed quercetin tablet with 10% lactose monohydrate exhibit faster dissolution time suggesting a promising stable quercetin tablets.
610 2 0 _aFaculty of Chemical and Process Engineering Technology
_xDissertations
650 0 _aUniversities and colleges
_xDissertations
650 0 _aTheses
_xDissertations
856 _uhttps://umpir.ump.edu.my/id/eprint/47701
942 _2lcc
_cPSM
999 _c105306
_d105312