000			02756ntm a2200349 i 4500
003			MY-KuUP
005			20260727125706.0
006			t|||||r|||| 000 0
007			ta
008			260727t20252025my a|||fr|||| 000 0 eng d
020			_aTHE0010768 (Local) _qHardback
040			_aUMPSA _beng _cUMPSA _erda
090			_aFTKKP .A366 2025 r Bc.
100	0		_aAinaa Alyaana Binti Omar, , , _eauthor.
245	1	0	_aFabrication and characterization of drug-loaded pla-starch nanofibers via electrospinning for biomedical application / _cAinaa Alyaana Binti Omar
264		1	_aKuantan, Pahang : _bUMPSA, _c2025
264		4	_c© 2025
300			_axi, 44 pages : _billustrations ;
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
347			_2rda _atext file _bPDF
500			_aFaculty of Chemical and Process Engineering Technology
502			_aFinal Year Report (Bachelor of Manufacturing Engineering Technology (Pharmaceutical) with Hons.) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025
504			_aInclude bibliographical reference
520	3		_aThe development of biodegradable nanofibers has drawn a lot of interest in biomedical applications because of its potential for tissue engineering as well as controlled drugs delivery. The electrospinning technique was employed in this work to fabricate and characterise polylactic acid (PLA)-starch-based nanofibers. The study investigates how fibre structure, degradation behaviour, and structural integrity are affected by varying starch concentrations. The best qualities, such as consistent fibre development, less bead-like formations, and appropriate degradation characteristics, were demonstrated by nanofibers with 0.16% w/v starch among all the investigated formulations. The successful incorporation of starch into the PLA matrix was verified by Fourier-Transform Infrared Spectroscopy (FTIR), while better fibre shape was established by Scanning Electron Microscopy (SEM) examination. Tests of swelling and weight loss showed that the modified formulation preserved controlled degradation, indicating that it is an appropriate choice for application in biomedical applications. The results indicate that PLA-starch nanofibers, especially at 0.16% w/v starch, have a lot of potential for application in wound healing and drug delivery systems. To improve nanofiber performance, more optimisations are recommended, such as long-term degradation study and improvements to the electrospinning parameters.
610	2	0	_aFaculty of Chemical and Process Engineering Technology _xDissertations
650		0	_aUniversities and colleges _xDissertations
650		0	_aTheses _xDissertations
856			_u
942			_2lcc _cPSM
999			_c105314 _d105320