000 02398nam a2200253 a 4500
001 vtls000045464
003 KUKTEM
005 20251114204425.0
008 100429t2009 my a f m 000 0 eng|d
020 _aTHE0003851(Local)
039 9 _a201905161541
_bshah
_c201107132316
_dVLOAD
_y201004291551
_zida
040 _aUMP
090 _aTP156.A35 R34 2009 rs Bc.
100 0 _aAbdul Rahim Mohd Yusoff
245 1 0 _aAntibiotic purification by using IMA adsorbents /
_cAbdul Rahim Bin Mohd Yusoff
246 3 _aAntibiotic purification by using IMA adsorbents
_h[electronic resource]
260 _aKuantan, Pahang :
_bUMP,
_c2009
300 _axix, 70 p. :
_bill. (some col.) ;
_c30 cm. +
_e1 computer file
502 _aProject paper (Bachelor of Chemical Engineering) -- Universiti Malaysia Pahang - 2009
504 _aBibliography : p. 65-67
520 3 _aThe intensity to achieve highly efficient and economical separation process can be seen in developing of various methods in the recent year. While in purification of antibiotic there are many methods use such as using High performance liquid chromatography (HPLC) and Counter-current chromatography (CCC). The purpose of this research is to develop immobilized metal ion affinity zeolite by using solid state ion exchange method to investigate the effect of pH, types of adsorbent using different metal into rifampicin adsorption capacity. Adsorption of rifampicin using zeolite has a greatly potential due to ability to scale up easily, and highly selective. It was found that the highest adsorption capacity for rifampicin occur at pH 8 with Zr-HBeta as adsorbent. H-beta zeolite give highest adsorption capacity because it has higher diameter size, surface area and pore volume compare to Y zeolite. Increasing the surface area and pore volume will give better chances of rifampicin to adsorb into adsorbent. Meanwhile, pH 8 gives the highest adsorption capacity because it is closer with the pKa2 value of rifampicin which is 7.9. While zirconium is the only transition metal containing both acidic and basic surface sites. So this will make it gives better adsorption capacity of rifampicin compare with ferum and nickel. The adsorption isotherm data of rifampicin was well correlated by the Langmuir model.
650 0 _aAdsorption
999 _aVIRTUA40
_c1785
_d1791
999 _aVTLSSORT0080*0200*0400*0900*1000*2450*2460*2600*3000*5020*5040*5200*6500*9992