000 04044nam a2200409 a 4500
001 vtls000025014
003 KUKTEM
005 20251117144516.0
008 080304t2005 gw a f bi 001 0 eng d
010 _a2006-436556
020 _a3527308377 (v. 1 : hbk. : alk. paper)
020 _a3527311300 (v. 2 : hbk. : alk. paper)
020 _a3527314350 (v. 3 : hbk. : alk. paper)
020 _a9783527314362 (v. 4 : hbk. : alk. paper)
020 _a9783527308378
020 _a9783527314355
039 9 _a201107131958
_bVLOAD
_c200908141414
_dVLOAD
_c200908141346
_dVLOAD
_c200908131738
_dVLOAD
_y200803040958
_znorsaini
040 _aUMP
090 _aQP551 .P76 2005
245 0 0 _aProtein degradation /
_c[edited by] R. John Mayer, Aaron Ciechanover, Martin Rechsteiner, eds.
260 _aWeinheim :
_bWiley-VCH,
_cc2005-c2008.
300 _a4 v. :
_bill. (some col.) ;
_c25 cm.
504 _aIncludes bibliographical references and index.
505 1 _av. 1. Ubiquitin and the chemistry of life. 1. Brief history of protein degradation and the ubiquitin system / Avram Hershko -- 2. N-terminal ubiquitination: no longer such a rare modification / Aaron Ciechanover -- 3. Evolutionary origin of the activation step during ubiquitin-dependent protein degradation / Hermann Schindelin -- 4. RING fingers and relatives: determinators of protein fate / Kevin L. Lorick ... [et al.] -- 5. Ubiquitin-conjugating enzymes / Michael J. Eddins and Cecile M. Pickart -- 6. The SCF ubiquitin E3 ligase / Leigh Ann Higa and Hui Zhang -- 7. The structural biology of ubiquitin-protein ligases / Ning Zheng and Nikola P. Pavletich -- 8. The deubiquitinating enzymes / Nathaniel S. Russell and Keith D. Wilkinson -- 9. The 26S proteasome / Martin Rechsteiner -- 10. Molecular machines for protein degradation / Matthias Bochtler ... [et al.] -- 11. Proteasome regulator, PA700 (19S regulatory particle) / George N. DeMartino and Cezary Wojcik -- 12. Bioinformatics of ubiquitin domains and their binding partners / Kay Hofmann -- 13. The COP9 signalosome: its possible role in the ubiquitin system --
505 0 _av. 2. The ubiquitin-proteasome system. 1. Molecular chaperones and the ubiquitin-proteasome system / Cam Patterson and Jörg Höhfeld -- 2. Molecular dissection of autophagy in the yeast Saccharomyces cerevisiae / Yoshinori Ohsumi -- 3. Dissecting intracellular proteolysis using small molecule inhibitors and molecular probes / Huib Ovaa ... [et al.] -- 4. MEKK1: dual function as a protein kinase and a ubiquitin protein ligase / Zhimin Lu and Tony Hunter -- 5. Proteasome activators / Andreas Förster and Christopher P. Hill -- 6. The proteasome portal and regulation of proteolysis / Monika Bajorek and Michael H. Glickman -- 7. Ubiquity and diversity of the proteosome system / Keiji Tanaka, Hideki Yashiroda, and Shigeo Murata -- 8. Proteasome-interacting proteins / Jean E. O'Donoghue and Colin Gordon -- 9. Structural studies of large, self-compartmentalizing proteases / Beate Rockel, Jürgen Bosch, and Wolfgang Baumeister -- 10. What the archaeal PAN - proteasome complex and bacterial ATP-dependent proteases can teach us about the 26S proteasome / Nadia Benaroudj, David Smith, and Alfred L. Goldberg -- 11. Biochemical functions of ubiquitin and ubiquitin-like protein conjugation / Mark Hochstrasser -- v. 4. The Ubiquitin-Proteasome System and disease.
650 0 _aProteins
_xMetabolism.
650 0 _aUbiquitin.
650 1 2 _aProteins
_xmetabolism.
650 2 2 _aCell Physiology.
650 2 2 _aUbiquitin
_xphysiology.
700 1 _aMayer, R. J.
700 1 _aCiechanover, Aaron J.
700 1 _aRechsteiner, Martin.
856 4 2 _3Contributor biographical information
_uhttp://www.loc.gov/catdir/enhancements/fy0644/2006436556-b.html
856 4 2 _3Table of contents only
_uhttp://www.loc.gov/catdir/enhancements/fy0644/2006436556-t.html
999 _aVIRTUA40
_c37761
_d37767
999 _aVTLSSORT0080*0100*0200*0201*0202*0203*0204*0205*0400*0900*2450*2600*3000*5040*5050*5051*6500*6501*6502*6503*6504*7000*7001*7002*8560*8561*9991