000 02711nam a2200265 a 4500
001 vtls000076026
003 KUKTEM
005 20251114204552.0
008 131112t2013 my da f m 000 0 eng d
020 _aTHE0002210(Local)
039 9 _a201905241001
_bshamsul
_y201311121506
_znabilah
040 _aUMP
090 _aQK495.L25 L38 2013 rs Bc.
100 1 _aLau, Mei Zhu
245 1 0 _aExtraction of phenolic compounds and flavonoids compounds from Orthosiphon Stamineus /
_cLau Mei Zhu
260 _aKuantan, Pahang :
_bUMP,
_c2013
300 _axv, 60 p. :
_bill. ;
_c30 cm. +
_e1 CD-ROM
502 _aProject paper (Bachelor of Chemical Engineering) -- Universiti Malaysia Pahang – 2013
504 _aBibliography : p. 57-59
520 3 _aPhenolic and flavonoids compounds present in Orthosiphon stamineus (OS) exhibit high antioxidant capacity. This research was conducted to compare ultrasonic-assisted extraction (UAE) and microwave-assisted extraction (MAE) with maceration and investigate effects of solvents (70%-30% v/v methanol-water, 70%-30% v/v propanol-water, 50%-50% v/v methanol-water, 50%-50% v/v propanol-water, water, methanol and propanol), extraction time, microwave power and extraction temperature on Rosmarinic acid and Sinensetin extraction yields from OS dried powder. The extraction yields were analyzed by using Ultra Performance Liquid Chromatography (UPLC) and were compared to standard calibration curve with their retention times. Results from Total Phenolic Content (TPC) were used to support UPLC result. By UAE, the highest yield for Rosmarinic acid could be obtained with following conditions: 70%-30% v/v Methanol-water as solvent with extraction time of 90 minutes at 60 ̊C. The highest yield for Rosmarinic acid that could be obtained by using MAE was with following conditions: 70%-30% v/v Methanol-water with extraction time of 120 s at 450 W. By UAE, the highest yield for Sinensetin could be obtained with following conditions: propanol as solvent with extraction time of 90 minutes at 60 ̊C. Meanwhile, the highest yield for Rosmarinic acid that could be obtained by using MAE was with following conditions, 70%-30% v/v Methanol-water with extraction time of 120 s at 450 W. UAE and MAE can replace maceration in extraction of phenolic compounds and flavonoids compounds since UAE and MAE had higher yields than maceration in shorter time. Recommendations suggested in order to obtain optimization of this research were to study more effects or parameters in both UAE and MAE.
650 0 _aLamiaceae
650 0 _aPhenols
650 0 _aFlavonoids
999 _aVIRTUA40
_c4268
_d4274
999 _aVTLSSORT0080*0200*0400*0900*1000*2450*2600*3000*5020*5040*5200*6500*6501*6502*9992