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001			vtls000038039
003			KUKTEM
005			20251117145415.0
008			090617t2008 flua f b 001 0 eng d
020			_a9780849390067 (hbk. : alk. paper)
020			_a0849390060 (hbk. : alk. paper)
039		9	_a201107132138 _bVLOAD _c200911111557 _dfauzi _c200908141632 _dVLOAD _c200908141606 _dVLOAD _y200906171150 _zshah
040			_aUMP
090			_aRS403 .C43 2008
245	0	0	_aChemistry and molecular aspects of drug design and action / _c[edited by] E.A. Rekka, P.N. Kourounakis
260			_aBoca Raton : _bCRC Press/Taylor & Francis, _cc2008
300			_axxii, 356 p. : _bill. ; _c25 cm.
504			_aIncludes bibliographical references and index
505	1		_aInflammatory mechanisms in Alzheimer's disease and other neurodegenerative disorders / Joseph Rogers ... [et al.] -- Treatment development strategies for Alzheimer's disease / Ernst Wülfert -- Lipoprotein-associated phospholipase A?b2?s as a new prognostic factor for coronary artery disease / Alexandros D. Tselepis -- New molecular targets for the prevention and treatment of gastrointestinal ulcers and inflammation / Sandor Szabo ... [et al.] -- Stress activates corticotropin releasing : factor signaling pathways : implication in functional bowel disorders / Yvette Taché -- Design, synthesis, and pharmacological evaluation of high-affinity and selectivity sigma-1 and sigma-2 receptor ligands / Jacques H. Poupaert -- Synthesis of biologically active taxoids / K.C. Nicolaou and R.K. Guy -- From the molecular pharmacology to the medicinal chemistry of cannabinoids / Didier M. Lambert -- An appraisal of fomocaines : current situation and outlook / Herbert Oelschläger and Andreas Seeling -- Ligands for the GABA recognition site at the GABAA receptor : structure-activity studies / Bente Frølund ... [et al.] -- Strategies for development of new lead structures for inhibition of acetylcholinesterase / Petra Kapkova ... [et al.] -- Discovery of potent and selective inhibitors of human aldosterone synthase (CYP11B2) : a new target for the treatment of congestive heart failure and myocardial fibrosis--a review / R.W. Hartmann ... [et al.] --
505	0		_aThiocarboxanilides : a new class of nonnucleoside reverse transcriptase inhibitors (NNRTIs) with great potential for the treatment of human immunodeficiency virus type 1 (HIV-1) infections / E. De Clercq, A. Karlsson, and J. Balzarini -- Histamine H?b3?s-receptor agonists and antagonists : chemical, pharmacological, and clinical aspects / Holger Stark and Walter Schunack -- Anti-inflammatory actions of flavonoids and structural requirements for new design / Theoharis C. Theoharides -- Molecular mechanisms of H?b2?sO?b2?s-induced DNA damage : the action of desferrioxamine / M. Tenopoulou, P.-T Doulias, and D. Galaris -- LNA (locked nucleic acid) and functionalized LNA : towards efficient gene targeting / Jesper Wengel -- The effect of diet on drug metabolism / K.J. Netter -- Cytochromes P450 in the metabolism and bioactivation of chemicals / Costas Ioannides -- In vitro methods to measure drug metabolism and drug interactions in drug discovery and development / O. Pelkonen ... [et al.] -- How to probe the sites of action of drug molecules / A. Makriyannis and F. Bitter -- Physicochemical profiling in early drug discovery : new challenges at the age of high-throughput screen and combinatorial chemistry / Bernard Faller -- Drug membrane interaction and its importance for drug efficacy / J.K. Seydel ... [et al.] -- The fight against AIDS : new avenues for inhibiting reverse transcriptase (RT), and old target / Maurizio Botta ... [et al.]
650		0	_aPharmaceutical chemistry
650		0	_aDrugs _xDesign
650	1	2	_aChemistry, Pharmaceutical
650	2	2	_aDrug Design
650	2	2	_aPharmacologic Actions
700	1		_aRekka, E. A.
700	1		_aKourounakis, P. N.
856	4	1	_3Table of contents only _uhttp://www.loc.gov/catdir/toc/ecip0712/2007010012.html
999			_aVIRTUA40 _c45591 _d45597
999			_aVTLSSORT0080020002010400090024502600300050405050505165006501650265036504700070018560*9991