000			03082nam a2200277 a 4500
001			vtls000057108
003			KUKTEM
005			20251117150123.0
008			111212t2011 flua f 001 0 eng d
020			_a9781439809648
020			_a143980964X
039		9	_a201202201556 _basmadi _y201112121449 _zshah
040			_aUMP
090			_aQP552.M46 P76 2011
245	0	0	_aProtein folding and metal ions : _bmechanisms, biology and disease / _cedited by Cláudio M. Gomes, Pernilla Wittung-Stafshede
260			_aBoca Raton, FL : _bCRC Press, _c2011
300			_axiv, 294 p. : _bill. ; _c25 cm.
504			_aIncludes bibliographical references and index
505	0		_aChapter 1. Metal Ions, Protein Folding, and Conformational States: An Introduction / Cláudio M. Gomes and Pernilla Wittung-Stafshede -- Chapter 2. The Folding Mechanism of c-Type Cytochromes / Carlo Travaglini-Allocatelli, Stefano Gianni, and Maurizio Brunori -- Chapter 3. The Mechanism of Cytochrome C Folding: Early Events and Kinetic Intermediates / Eefei Chen, Robert A. Goldbeck, and David S. Kliger -- Chapter 4. Stability and Folding of Copper-Binding Proteins / Irina Pozdnyakova and Pernilla Wittung-Stafshede -- Chapter 5. Iron-Sulfur Clusters, Protein Folds, and Ferredoxin Stability / Sónia S. Leal and Cláudio M. Gomes -- Chapter 6. Folding and Stability of Myoglobins and Hemoglobins / David S. Culbertson and John S. Olson -- Chapter 7. Frataxin: An Unusual Metal-Binding Protein in Search of a Function / Annalisa Pastore -- Chapter 8. Mechanism of Human Copper Transporter Wilson's Disease Protein -- Amanda Barry, Zara Akram, and Svetlana Lutsenko -- Chapter 9. a-Synuclein and Metals -- Aaron Santner and Vladimir N. Uversky -- Chapter 10. Zinc and Misfolding / James S. Butler and Stewart N. Loh -- Chapter 11. The Octarepeat Domain of the Prion Protein and Its Role in Metal Ion Coordination and Disease / Glenn L. Millhauser -- Chapter 12. Metallopeptides as Tools to Understand Metalloprotein Folding and Stability / Brian R. Gibney -- Chapter 13. The Folding Landscapes of Metalloproteins / Patrick Weinkam and Peter G. Wolynes
520			_a"Interest in the uses and applications of metallo-chemistry in the life sciences continues to expand. This book provides a broad overview of metals and protein folding. It addresses fundamental aspects of the folding, stability, and design of metal binding proteins and peptides along with biological aspects related to the action of metallochaperones. The text features practical information related to methodologies, particular techniques, and bibliographic references. Readers will gain the molecular basis for protein-metal interactions and a good perspective on the applications of protein coordination chemistry in life sciences and biotechnology"--Provided by publisher
650		0	_aMetalloproteins
650		0	_aProtein folding
700	1		_aGomes, Cláudio M.
700	1		_aWittung-Stafshede, Pernilla
999			_aVIRTUA40 _c51843 _d51849
999			_aVTLSSORT0080*0200*0201*0400*0900*2450*2600*3000*5040*5050*5200*6500*6501*7000*7001*9991