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008 111210t2011 flua f 001 0 eng d
020 _a9781439810712
020 _a1439810710
039 9 _a201203011239
_bida
_c201202211242
_dasmadi
_y201112101846
_zshah
040 _aUMP
090 _aQP551 .K47 2011
100 1 _aKessel, Amit
245 1 0 _aIntroduction to proteins :
_bstructure, function, and motion /
_cAmit Kessel and Nir Ben-Tal
260 _aBoca Raton, FL :
_bCRC Press,
_c2011
300 _axxvii, 626 p. :
_bill. (some col.) ;
_c27 cm.
490 0 _aChapman & Hall/CRC mathematical and computational biology series
504 _aIncludes bibliographical references and index
520 _a"The book aims to provide the reader with a detailed description of protein structure and dynamics, combined with an in-depth discussion of the relationship between both these aspects and protein function. Adopting the structural-biophysical approach, we discuss these in relation to molecular interactions and thermodynamic changes that transpire in this highly complex system. There are several types of textbooks describing protein structure and function. Biochemistry textbooks emphasize the functional aspect of proteins and provide a rather general description of structure and structure-function relationship (SFR). Structural Biology textbooks provide an extensive description of protein structure and also refer to SFR with varying degrees of detail. However, energy-related aspects are often avoided. Molecular biophysics textbooks focus on molecular interactions and thermodynamic aspects of protein structure, but tend to lack detailed description of structural and dynamic aspects, as well as SFR. Our book refers to all of the a fore mentioned aspects and attempts to provide a unified view. Our energy-oriented approach is manifested throughout the book, whether we discuss structure, dynamics or specific functions of proteins. An extensive discussion of the energetics of protein structure is also given in a chapter dedicated to this topic"--Provided by publisher
650 0 _aProteins
650 0 _aProteins
_xStructure-activity relationships
650 0 _aPhysical biochemistry
700 1 _aBen-Tal, Nir
999 _aVIRTUA40
_c56005
_d56011
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