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008 160310t2015 my da f ab m 000 0 eng d
020 _aTHE0000211(Local)
039 9 _a201905141042
_bnazirah
_c201710161607
_daishah
_y201603101123
_zasma
040 _aUMP
090 _aFIST .T39 2015 r Thesis
100 0 _aTawfiqullah Ayoubi
245 1 0 _aStochastic modelling of time delay for solvent production by Clostridium Acetobutylicum P262 /
_cTawfiqullah Ayoubi
260 _aKuantan, Pahang :
_bUMP,
_c2015
300 _axvii, 137 p. :
_bill. col. ;
_c30 cm. +
_e1 CD-ROM
500 _aFaculty of Industrial Sciences and Technology
502 _aThesis (Master of Science (Mathematics)) -- Universiti Malaysia Pahang – 2015
504 _aBibliography : p. 110-119
520 3 _aOrdinary differential equations (ODEs) and stochastic differential equations (SDEs) are widely used to model biological systems in the last decades. In both types of equations, the unknown function and its derivatives are evaluated at the same instant time, t. However, many of the natural phenomena do not have an immediate effect from the moment of their occurrence. For instance, a patient shows symptoms of an illness days or even weeks after the day in which they were infected. The dynamics of the systems differ if the corresponding characteristic equations involve time delay. Therefore, ODEs and SDEs which are simply depending on the present state are insufficient to explain this process. Such phenomenon can be modelled via stochastic delay differential equations (SDDEs). Batch fermentation process is one of the systems which subject to the presence of uncontrolled fluctuation and delayed feedback. ODEs and SDEs are not capable to model uncontrolled fluctuation and delayed feedback in fermentation process. It is necessary to model this process via SDDEs. Thus, this research is carried out to propose a stochastic model with delay effect for cell growth and solvent production of acetone and butanol by Clostridium Acetobutylicum P262 in fermentation process. The kinetic parameters of the results model are estimated via maximum likelihood method. The analytical solutions of this model is hard to be found, hence numerical method of 4-stage stochastic Runge-Kutta (SRK4) provide a way to simulate the solutions of the model. The RK4 and SRK4 methods are translated into C languages to obtain the numerical solutions of mathematical model for the cell growth concentration and solvents production. The experimental data is used to validate the results. The results indicate that the most suitable model to explain the solvent production by Clostridium Acetobutylicum P262 in fermentation process is SDDEs
610 2 0 _aFaculty of Industrial Sciences and Technology
_xDissertations
650 0 _aUniversities and Colleges
_xDissertations
650 0 _aTheses
856 4 0 _uhttp://ecollib.ump.edu.my/3545/
_zLibrary access only
999 _aVIRTUA40
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