000 02958ntm a2200373 i 4500
001 vtls000102925
003 KUKTEM
005 20251117113357.0
008 180205s2017 my a f am 000 0 eng d
020 _aTHE0000930(Local)
039 9 _a201905271020
_bnazirah
_c201802201117
_dsaini
_c201802051239
_dsaini
_y201802051126
_zsaini
040 _aUMP
_beng
_cUMP
_erda
090 _aFKKSA .K44 2017 r Bc.
100 1 _aKee, Keing Lee,
_eauthor.
245 1 0 _aExtraction of polyphenol from phyllanthus niruri /
_cKee Keing Lee
264 1 _aKuantan, Pahang :
_bUMP,
_c2017
264 4 _c© 2017
300 _axiv, 101 pages :
_billustrations (some color) ;
_c30 cm. +
_e1 CD-ROM
336 _atext
_2rdacontent
336 _atext
_2rdacontent
337 _aunmediated
_2rdamedia
337 _acomputer
_2rdamedia
338 _avolume
_2rdacarrier
338 _acomputer disc
_2rdacarrier
347 _atext file
_bPDF
_2rda
500 _aFaculty of Chemical & Natural Resources Engineering
502 _aProject Paper (Bachelor of Chemical Engineering) -- Universiti Malaysia Pahang – 2017
504 _aIncludes bibliographical references
520 3 _aPhyllanthus niruri which is also known as Dukung Anak is a plant which contain miscellaneous bioactive components which provide the medical effects such as antioxidant, anti-cancer and treating Hepatitis-B. Extraction is a common method to obtain bioactive component from plant materials therefore this research is to elucidate the effect of solvents types and investigate the performance of different type extraction method on P.Niruri. Ultrasonic assisted extraction and microwave assisted extraction methods were studied because there is no previous work found in literature. Analysis such as Total Phenolic Content, Total Flavonoids Content, Ultra-Performance Liquid Chromatography were carried out throughout the research. From the works, it is found that highest yield of phyllanthin with 4.56mg Phy/g DW was obtained with 20% aqueous Isopropanol whereas the quercetin with the highest yield, 10.14mg Que/g DW in 20% aqueous ethanol and the highest yield 15.44mg GAE/g DW of gallic acid was obtained by using water. Central Composite Design analysis shown that microware assisted extraction with 250W power, 3.62 minutes and 52.58% ethanol concentration obtain the optimum yield of polyphenol extraction of 83.70%. In conclusion, the yield of bioactive component is highly dependent on solvent polarity used in extraction and microwave extraction method provides a fast extraction without significantly compromising the extraction yield compare to ultrasonic assisted extraction.
610 2 0 _aFaculty of Chemical & Natural Resources Engineering
_xDissertations
650 0 _aUniversities and Colleges
_xDissertations
650 0 _aTheses
999 _aVIRTUA40
_c7629
_d7635
999 _aVTLSSORT0080*0200*0400*0900*1000*2450*2640*2641*3000*3360*3361*3370*3371*3380*3381*3470*5000*5020*5040*5200*6100*6500*6501*9992